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Search Result

Search Results for " bestatin "

Targets

Others

21

Compounds

3

Natural Products

1

Reagents

Cat No. Product Name Synonyms Targets
T18612 Bestatin-amido-Me PROTAC IAP binding moiety 1 Others
Bestatin-amido-Me, a derivative of Bestatin, acts as an IAP ligand and interacts with ABL inhibitor through a linker to produce SNIPER[1].
T38470 Obestatin(human)
Obestatin (human) is a 23-amino acid amidated peptide that interacts with GPR39 to regulate appetite and gastrointestinal motility. Its properties also make it suitable for weight loss. Nonetheless, Obestatin (human) is ...
TP2279L Obestatin (rat) acetate GHSR
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin (rat) acetate has anti-inflammatory, anti-myocardial infarction and antioxidant properties. Obestatin (rat) acetate supp...
T29436 4-Hydroxybestatin
4-Hydroxybestatin is a major active metabolite of bestatin.
T25573 Ketomethylenebestatin
Ketomethylenebestatin is a carba-analog of bestatin，the aminopeptidase (AP) inhibitor. Ketomethylenebestatin is 10 fold less effective as an inhibitor of aminopeptidases than bestatin.
T71626 Epibestatin Hydrochloride
Epibestatin Hydrochloride is a stabilizer of 14-3-3 PPIs, as well as a diastereoepimer of aminopeptidase inhibitor bestatin.
TP2279 Obestatin(rat) Obestatin (rat) Others
Endogenous peptide that suppresses food intake and body weight-gain
T81625 Obestatin(human) TFA
Obestatin(human) TFA, an endogenous peptide originating from the same prepropeptide as ghrelin, is known to suppress food intake and reduce weight gain in rats.
T81626 Obestatin(11-23)mouse, rat
Obestatin(11-23)mouse, rat is a polypeptide that regulates energy balance and suppresses appetite by reducing food consumption, body weight, and jejunal contractions in rodents [1].
T35787 Obestatin (human) (trifluoroacetate salt)
Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.1It binds to the orphan receptor GPR39 (Kd...
T75901 Obestatin(rat) TFA
Obestatin(rat) TFA is a cpeptide derived from the Ghrelin gene, consisting of 23 amino acids. This compound modulates physiological processes by suppressing food intake, inhibiting jejunal contraction, and reducing body-...
T14288 Androstanolone acetate Others
Androstanolone acetate is a compound that functions as an androgen ligand, specifically targeting the androgen receptor (AR). It binds to the cIAP1 ligand Bestatin through a linker, resulting in the formation of PROTACs[...
T17545 Biotin-BS Others
Biotin-BS is a chemical compound composed of two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and biotin. These ligands are interconnected through linkers. MeBS serves as a ligand specifically for the cellular inhi...
T18650 Ch55-O-C3-NH2 RAR ligand 1 Others
Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts with cIAP1 ligand Bestatin to form SNIPER[1].
T18684 SNIPER(ABL)-013 Others
SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 20 μM[1].
T18693 SNIPER(ABL)-049 Others
SNIPER(ABL)-049, a compound that conjugates Imatinib (ABL inhibitor) with Bestatin (IAP ligand) through a linker, effectively reduces BCR-ABL protein levels, demonstrating a DC50 of 100 μM[1].
T18687 SNIPER(ABL)-020 Others
SNIPER(ABL)-020 is a chemical compound consisting of Dasatinib, an ABL inhibitor, and Bestatin, an IAP ligand, conjugated with a linker. This compound effectively reduces the BCR-ABL protein[1].
T18691 SNIPER(ABL)-044 Others
SNIPER(ABL)-044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a DC50 value of 10 μM[1].
T17706 BzNH-BS Others
BzNH-BS is a chemical compound comprising two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide. The ligands are interconnected through linkers. MeBS functions as a ligand for cIAP1, a ubiquitin ligase...
T17733 ATRA-hydroxyimino CRABP-II ligand 1 Others
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation o...
T17940 Estrone-N-O-C1-amido ERα ligand 1 Others
Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-O-C1-amido (ERα ligand 1) forms a complex with the cIAP1 li...
Cat No. Product Name Synonyms Targets
T1257 Bestatin Ubenimex Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...
T3529 Bestatin hydrochloride Ubenimex hydrochloride Integrin , Aminopeptidase , Antibacterial , Antibiotic
Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.
T62258 Bestatin trifluoroacetate
Bestatin trifluoroacetate (Ubenimex trifluoroacetate) is a CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor that is often used in cancer research.

Natural Products

Bestatin
T1257
Synonym: Ubenimex
Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR
Bestatin hydrochloride
T3529
Synonym: Ubenimex hydrochloride
Target: Integrin, Aminopeptidase, Antibacterial, Antibiotic
Bestatin trifluoroacetate
T62258
Synonym:
Target:

Reagents


Protease Inhibitor Cocktail
(EDTA-Free, 100× in DMSO)
Catalog No. C0001
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