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868540-17-4

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    TargetMol | All_Pathways
Carfilzomib
PR-171
T1795868540-17-4
Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome. Carfilzomib has antitumor activity and may be used to treat multiple myeloma.
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TargetMol | Citations Cited
Carfilzomib-d8
TMID-10141537187-53-3
Carfilzomib-d8 is the deuterated form of Carfilzomib. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.
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