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1535187-91-7

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
MC3343
MC 3343
T2033451535187-91-7
MC3343, a DNMT inhibitor with IC50 values of 5.7 μM for DNMT1 and 1.7 μM for DNMT3a, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2 M phase and induces osteogenic differentiation by specifically re-expressing genes that regulate this physiological process, and is able to show synergistic effects in combination with adriamycin and cisplatin (CDDP).
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