T6533 |
Hexestrol
|
84-16-2
|
100%
|
|
Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
|
T39710 |
ARV-471
|
2229711-68-4
|
97.15%
|
|
ARV-471 is a orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
|
T2882 |
Genistin
|
529-59-9
|
97.65%
|
|
Genistin is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anti...
|
T15788 |
LSZ-102
|
2135600-76-7
|
97.84%
|
|
LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.
|
T0301 |
Ethisterone
|
434-03-7
|
97.96%
|
|
Ethisterone is a progestogen hormone.
|
T5S0543 |
Isocurcumenol
|
24063-71-6
|
98%
|
|
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
|
T7299 |
β-Estradiol 17-acetate
|
1743-60-8
|
98%
|
|
beta-estradiol 17-acetate is a metabolite of estradiol.
|
T0035 |
Dienestrol
|
84-17-3
|
98%
|
|
Dienestrol is a synthetic and nonsteroidal estrogen, which is an estrogen receptor agonist. Estrogens can increase a normal clear discharge from the vagina and m...
|
T2544 |
Bazedoxifene acetate
|
198481-33-3
|
98%
|
|
Bazedoxifene acetate is a novel selective estrogen receptor modulator (SERM).
|
T7313 |
Enclomiphene citrate
|
7599-79-3
|
98%
|
|
Enclomiphene citrate is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
|
T1549 |
Raloxifene hydrochloride
|
82640-04-8
|
98%
|
|
Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estroge...
|
T5624 |
Bisphenol B
|
77-40-7
|
98%
|
|
Bisphenol B has a binding affinity for estrogen receptors.
|
T5633 |
H3B-5942
|
2052128-15-9
|
98%
|
|
H3B-5942 belongs to a class of ERα antagonists referred to as selective estrogen receptor covalent antagonists (SERCA).
|
T5835 |
PROTAC ERRα ligand 2
|
2306388-57-6
|
98%
|
|
PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)
|
T5531 |
GSK-4716
|
101574-65-6
|
98%
|
|
GSK4716 is an ERRβ/γ agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand
|
T1571 |
Estriol
|
50-27-1
|
98.05%
|
|
Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
|
T12832 |
Amcenestrant
|
2114339-57-8
|
98.13%
|
|
SAR439859 is an orally active, nonsteroidal and selective degrader of estrogen receptor (SERD). SAR439859 is a potent antagonist of ER (with an EC50 of 0.2 nM fo...
|
T15249 |
Estrogen receptor modulator 1
|
63676-22-2
|
98.14%
|
|
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active a...
|
T15364 |
G-1
|
881639-98-1
|
98.14%
|
|
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM).
|
T20744 |
Nylestriol
|
39791-20-3
|
98.16%
|
|
Nylestriol is an agonist of estrogen receptor.
|