Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T3542	BVT-14225	376638-65-2	98.14%
T3542	BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).
T9003	CVT-11127	1018674-83-3	98.15%
T9003	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
T1979	AVN-944	297730-17-7	98.19%
T1979	AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T1809	AGI-6780	1432660-47-3	98.19%
T1809	AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
T2901	Daidzin	552-66-9	98.28%
T2901	Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T23533	WIN 18446	1477-57-2	98.41%
T23533	inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
T11765	KPLH1130	906669-07-6	98.43%
T11765	KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and att...
T5S0620	3-Dehydrotrametenolic acid	29220-16-4	98.5%
T5S0620	1. Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new t...
T0494	Tetramisole hydrochloride	5086-74-8	98.6%
T0494	Tetramisole is used as an anthelmintic.
T2447	AZD7545	252017-04-2	98.69%
T2447	AZD7545 is a potent PDHK inhibitor.
T8640	G6PDi-1	2457232-14-1	98.69%
T8640	G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.
T11029	HDHODH-IN-5	2029049-77-0	98.70%
T11029	hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).
T17224	VER-246608	1684386-71-7	98.88%
T17224	VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK...
T38683	SCD1 inhibitor-3	1282606-48-7	98.95%
T38683	SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II...
T2043	Mutant IDH1-IN-1	1355326-21-4	98.98%
T2043	Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.
T22253	AG-120 (racemic)	1448346-63-1	98.99%
T22253	AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic acti...
T2650	MK-8245	1030612-90-8	99%
T2650	MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.
T2121	SW033291	459147-39-8	99.02%
T2121	SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
T10525	SCD1 inhibitor-4	1295541-87-5	99.02%
T10525	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
T11025	HDHODH-IN-3	1644156-80-8	99.05%
T11025	hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.