T3542 |
BVT-14225
|
376638-65-2
|
98.14%
|
|
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).
|
T9003 |
CVT-11127
|
1018674-83-3
|
98.15%
|
|
CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
|
T1979 |
AVN-944
|
297730-17-7
|
98.19%
|
|
AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
|
T1809 |
AGI-6780
|
1432660-47-3
|
98.19%
|
|
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.
|
T2901 |
Daidzin
|
552-66-9
|
98.28%
|
|
Daidzin is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
|
T23533 |
WIN 18446
|
1477-57-2
|
98.41%
|
|
inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
|
T11765 |
KPLH1130
|
906669-07-6
|
98.43%
|
|
KPLH1130 improves glucose tolerance in HFD-fed mice. KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and att...
|
T5S0620 |
3-Dehydrotrametenolic acid
|
29220-16-4
|
98.5%
|
|
1. Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new t...
|
T0494 |
Tetramisole hydrochloride
|
5086-74-8
|
98.6%
|
|
Tetramisole is used as an anthelmintic.
|
T2447 |
AZD7545
|
252017-04-2
|
98.69%
|
|
AZD7545 is a potent PDHK inhibitor.
|
T8640 |
G6PDi-1
|
2457232-14-1
|
98.69%
|
|
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.
|
T11029 |
HDHODH-IN-5
|
2029049-77-0
|
98.70%
|
|
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).
|
T17224 |
VER-246608
|
1684386-71-7
|
98.88%
|
|
VER-246608 is an effective and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (IC50s: 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK...
|
T38683 |
SCD1 inhibitor-3
|
1282606-48-7
|
98.95%
|
|
SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II...
|
T2043 |
Mutant IDH1-IN-1
|
1355326-21-4
|
98.98%
|
|
Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.
|
T22253 |
AG-120 (racemic)
|
1448346-63-1
|
98.99%
|
|
AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic acti...
|
T2650 |
MK-8245
|
1030612-90-8
|
99%
|
|
MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.
|
T2121 |
SW033291
|
459147-39-8
|
99.02%
|
|
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
|
T10525 |
SCD1 inhibitor-4
|
1295541-87-5
|
99.02%
|
|
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
|
T11025 |
HDHODH-IN-3
|
1644156-80-8
|
99.05%
|
|
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.
|