Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T13356	XEN723	1072803-08-7	99.54%
T13356	XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
T1335	Mycophenolic acid	24280-93-1	99.52%
T1335	Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
T25209	CB29	315239-63-5	99.51%
T25209	CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
T5427	GSK1940029	1150701-66-8	99.48%
T5427	GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.
T11238L	Etamicastat hydrochloride	677773-32-9	99.48%
T11238L	Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
T2970	Rotenone	83-79-4	99.48%
T2970	Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the produc...
T0361	Isovaleramide	541-46-8	99.47%
T0361	Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.
T1485	Methotrexate	59-05-2	99.46%
T1485	Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive act...
T1919	Tenovin-1	380315-80-0	99.44%
T1919	Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.
T7835	CM10	692269-09-3	99.44%
T7835	CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.
T21089	Nitrophenide	537-91-7	99.43%
T21089	Nitrophenide (3,3'-Dinitrodiphenyl disulfide) inhibits mannitol-1-phosphate dehydrogenase (M1PDH), which catalyzes the committed enzymatic step in the mannitol c...
T60149	11β-HSD1-IN-11	859721-81-6	99.42%
T60149	11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM...
T8767	PfDHODH-IN-2	425629-94-3	99.37%
T8767	PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used ...
T23903	CM037	896795-60-1	99.34%
T23903	CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminate gyn...
T0732	Benzyl alcohol	100-51-6	99.34%
T0732	Benzyl alcohol (Benzenemethanol), a colorless liquid, is an aromatic alcohol with a mild pleasant aromatic odor.
T0414	D-Mannitol	69-65-8	99.34%
T0414	D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the bod...
T11028	HDHODH-IN-4	1644156-56-8	99.31%
T11028	hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits mea...
T9859	SW209049	1673558-59-2	99.31%
T9859	SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.
T23911	CPS-11	145945-21-7	99.30%
T23911	CPS-11 (N-(Hydroxymethyl)thalidomide) is a Thalidomide analogue that has significant antitumor activity and exhibits a wider range of activity and highly potent ...
T28424	PKUMDL-WQ-2101	304481-72-9	99.28%
T28424	PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.