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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
T1111 Pralidoxime Chloride 51-15-0 98%
Pralidoxime chloride is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, use...
TN1858 Leptomerine 22048-97-1 98%
Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.
T0204 Protriptyline hydrochloride 1225-55-4 98%
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
TN2130 Manghaslin 55696-57-6 98%
Manghaslin has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also sh...
T8585 TA-03 5778-80-3 98%
TA-03 is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
TN2131 Questin 3774-64-9 98%
Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V. harveyi, V. anguillarum, V. cholera...
T14194 β-NETA 31059-54-8 98%
α-NETA is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (...
T15949 Mahanimbine 21104-28-9 98%
Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an orally active alkaloid extracted from Murraya koenigii. Bifidobacterium bifidum...
TN2217 Sophoflavescenol 216450-65-6 98%
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , the...
Pralidoxime Chloride
T1111
Pralidoxime chloride is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, use...
Leptomerine
TN1858
Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.
Protriptyline hydrochloride
T0204
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
Manghaslin
TN2130
Manghaslin has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also sh...
TA-03
T8585
TA-03 is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
Questin
TN2131
Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V. harveyi, V. anguillarum, V. cholera...
β-NETA
T14194
α-NETA is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (...
Mahanimbine
T15949
Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an orally active alkaloid extracted from Murraya koenigii. Bifidobacterium bifidum...
Sophoflavescenol
TN2217
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , the...
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