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Results for "
yj1206
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products2
YJ1206
YJ 1206
T2008453053716-98-3
YJ1206 is a highly potent and selective CDK12 13 PROTAC degrader (IC50 =12.55 nM) with the advantages of oral administration and low toxicity, which triggers gene-length-dependent transcription elongation defects, leading to DNA damage and cell-cycle arrest, and inhibits the proliferation of a subpopulation of prostate cancer cells. YJ1206 can synergize with AKT pathway inhibitors to effectively inhibit prostate cancer.
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E3 Ligase Ligand-linker Conjugate 130
T201742
E3 Ligase Ligand-linker Conjugate 130 is an E3 ubiquitin ligase ligand-linker conjugate (E3 Ligase Ligand-linker conjugate) used in the synthesis of YJ1206.
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