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p53 and mdm2 proteins-interaction-inhibitor

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
T12350
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a compound that inhibits the interaction between p53 and MDM2 proteins.
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p53 and MDM2 proteins-interaction-inhibitor (racemic)
p53-and-mdm2-proteins-interaction-inhibitor-racemic
T12351939983-14-9
The racemic p53 and MDM2 proteins-interaction-inhibitor is an inhibitor of the interaction between p53 and MDM2 proteins.
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3-6 months
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MDMX/MDM2-IN-2
T78699
MDMX MDM2-IN-2 is a potent dual inhibitor of p53-MDM2 MDMX, with dissociation constants (Kis) of 0.23 μM for MDM2 and 2.45 μM for MDMX. It disrupts the interaction between p53 and MDM2 proteins, reinstating p53 functionality to induce cell cycle arrest and apoptosis. Additionally, this compound impedes cell migration and invasion, exhibiting notable antitumor activity [1].
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