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lesinurad

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Lesinurad
RDEA594
T6875878672-00-5
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.
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Lesinurad sodium
RDEA-594 sodium, RDEA594 sodium, RDEA 594 sodium
T213011151516-14-1
Lesinurad sodium (RDEA594 sodium) is a selective inhibitor of uric acid reabsorption and is used in the study of cardiovascular diseases.
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7-10 days
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URAT1 inhibitor 4
T726322700292-02-8
URAT1 Inhibitor 4, derived from Lesinurad, is a potent, orally active inhibitor of URAT1 with an IC50 value of 7.56 μM, demonstrating greater in vivo urate-lowering efficacy than Lesinurad [1].
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6-8 weeks
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URAT1 inhibitor 6
T791762244807-49-4
URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone, respectively. This compound is utilized in the study of inflammation [1].
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8-10 weeks
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