fibroblast growth factor 15

Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.

Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15 19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 111.6 kDa and the accession number is Q86Z14.

Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15 19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.