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denspm

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
ZD-6888
T70803138620-04-9
ZD-6888 is an angiotensin type 1 receptor antagonist potentially for the treatment of hypertension.
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6-8 weeks
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Diethylnorspermine HCl
T9640156886-85-0In house
Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.
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N1,N11-Diethylnorspermine
T60348121749-39-1
N1,N11-Diethylnorspermine (DENSPM), a spermine analog, serves as a potent anticancer agent by activating polyamine catabolism, which in turn triggers cytochrome c release from mitochondria and activates caspase 3. This process ultimately leads to the death of glioblastoma multiforme (GBM) cells by inducing spermidine spermine N1-acetyltransferase (SSAT) activity along with the production of H2O2 [1] [2] [3].
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6-8 weeks
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Diethylnorspermine HBr
T708051384898-58-1
Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine spermine N1-acetyltransferase (SSAT). A designed polyamines (PAs) analog which induces cell cycle arrest, inhibits proliferation and induces apoptosis in melanoma, breast, prostate, lung and colon cancer cells..
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1-2 weeks
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