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Results for "

cd 177

" in TargetMol Product Catalog

Recombinant Protein
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CD177 Protein, Human, Recombinant (His)

PRV-1, PRV1, Polycythemia Rubra Vera Protein 1, NB1 GP, NB1 Glycoprotein, NB1, Human Neutrophil Alloantigen 2a, HNA-2a, CD177 Antigen, CD177

TMPJ-00541

CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR CD59 Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.

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7-10 days

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SPR-compatible buffer

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CD177 Protein, Human, Recombinant (GST & His)

PRV1, Polycythemia rubra vera protein 1 (PRV-1), NB1 glycoprotein (NB1 GP), NB1, Human neutrophil alloantigen 2a (HNA-2a), CD177 antigen, CD177

TMPH-01070

Expression system: E. coli
Length: 22-321, Partial
Activity: Not Tested

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20 days

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Buffer-exchangeable

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