Tween

Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase.

Tween-20(Polysorbate 20) ,sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives, is used in the formulation of biotherapeutic products for both preventing surface adsorption and as a stabilizer against protein aggregation.

Tween 85 is a nonionic surfactant classified under ethoxylated sorbitan esters. It serves as an emulsifier and solubilizer across various industries, including pharmaceuticals, cosmetics, and food. Owing to its ability to blend oily and aqueous components, it is often utilized in the formulation of creams, lotions, and ointments. Additionally, it functions as a pigment dispersant in the production of paints and coatings.

Tween 65 is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Tween 40 is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent, exhibiting moderate antibacterial effects with MIC values of 6.3 and 11 μM in minimal GAST Fe and rich 7H9 ADC Tween media, respectively.

OH-Chol is a cationic cholesterol derivative. OH-Chol, as a component of lipoplexes with [DOPE], has been used for siRNA delivery and gene silencing in MCF-7 cells and in mice via intravenous injection, resulting in lipoplex accumulation in the liver. Additionally, it has been employed in cationic nanoparticles with [Tween 80] to transfect pDNA and siRNA into PC3 mouse xenografts via intratumoral injection and with [Tween 80] and [folate-PEG2000-DSPE] in a KB mouse xenograft model for intratumoral gene delivery.

O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.

m-PEG-thiol (MW 750) is utilized to modify thiolated DNA for the synthesis of gold nanorods (AuNR). Using an mPEG-SH Tween 20 assisted method (where Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface), thiolated DNA can be loaded onto the AuNR. DNA AuNR has been widely applied in nanostructure assembly, gene therapy, biosensing, and drug delivery.

m-PEG-thiol (MW 1000) is utilized for the thiolation of DNA and is essential in the synthesis of gold nanorods (AuNR). Using an mPEG-SH Tween 20-assisted method, where Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface, thiolated DNA can be loaded onto AuNR. DNA AuNRs have been widely applied in nanostructure assembly, gene therapy, biosensing, and drug delivery.

m-PEG-thiol (MW 3400) is utilized for modifying thiolated DNA and synthesizing gold nanorods (AuNR). Through the mPEG-SH Tween 20 assisted method (where Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface), thiolated DNA can be loaded onto AuNR. DNA AuNR has been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

m-PEG-thiol (MW 350) can modify thiolated DNA for the synthesis of gold nanorods (AuNR). Thiolated DNA can be loaded onto AuNR by the mPEG-SH Tween 20-assisted method (repeated replacement of CTAB on the AuNR surface using Tween 20 and mPEG-SH).DNA AuNR has been used in a wide range of applications in nanostructure assembly, gene therapy, biosensing, and drug delivery.

L-Histidine buffer, Sterile, is a commonly used antibody storage buffer with a composition of 20 mM L-Histidine, 240 mM Sucrose, 150 mM NaCl, and 0.05% Tween 80, pH 5.8.

m-PEG-thiol (MW 550) is used to modify thiolated DNA for the synthesis of gold nanorods (AuNR). The mPEG-SH Tween 20 assisted method (involving repeated replacement of CTAB on the AuNR surface with Tween 20 and mPEG-SH) enables the loading of thiolated DNA onto AuNR. DNA AuNR has been extensively utilized in nanostructure assembly, gene therapy, biosensing, and drug delivery.