Search Result

Search Results for " plp "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1312L	[SER140]-PLP(139-151) acetate	[SER140]-PLP(139-151) acetate (122018-58-0 Free base)	Others
	[SER140]-PLP(139-151) acetate is a peptide fragment from myelin proteolipid protein (PLP).		Others
TP1282	PLP (139-151)	PLP 139-151
	PLP (139-151) is amino acid residue residue 139 to 151 of myelin proteolipid protein (PLP). This peptide is used to induce relapsing-remitting (RR)-EAE model.
TP1402	[SER140]-PLP(139-151) TFA (122018-58-0 free base)	[SER140]-PLP(139-151) TFA
	[SER140]-PLP(139-151) (TFA) is a polypeptide fragment of the myelin lipid protein.
TP1312	[SER140]-PLP(139-151)
	[SER140]-PLP(139-151) is a polypeptide fragment of the lipid protein of myelin.
T81438	PLP (180-199)
	PLP (180-199), an active biological peptide comprising amino acids 180-199 of myelin proteolipid protein (PLP)—the predominant myelin protein in the central nervous system (CNS)—is utilized in research focused on multipl...
T81439	PLP (178-191)
	PLP (178-191), an immunodominant encephalitogenic epitope from the proteolipid protein (PLP) fragment spanning amino acids 178 to 191, plays a pivotal role in SJL mice. It initiates disease onset earlier compared to the ...
T64674	Plp(139-151) trifluoroacetate
	Plp(139-151) trifluoroacetate is a useful organic compound for research related to life sciences and the catalog number is T64674.
T83690	[Leu144, Arg147]-PLP (139-151) TFA	[Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
	[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing m...
T12502	PLpro inhibitor		SARS-CoV
	PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)		SARS-CoV
T78704	PLpro/RBD-IN-1		SARS-CoV
	PLpro/RBD-IN-1 is a dual inhibitor of SARS-CoV-2 PLpro and the spiny protein RBD, with anti-novel coronavirus activity, and is seen for the study of viral infections.		SARS-CoV
T62991	Mpro/PLpro-IN-1
	Mpro/PLpro-IN-1 (Compound 29) is a dual-acting inhibitor of SARS-CoV-2 protease.Mpro/PLpro-IN-1 is also a potent inhibitor of Mpro/PLpro, with micromolar inhibition of M pro (IC50:1.72 μM) and submicromolar inhibition of...
T61500	PLP_Snyder530
	PLP_Snyder530 is a potent papain-like protease (PL pro ) inhibitor. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-C...
T3578L	Pyridoxal calcium phosphate
	Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), known as an active form of vitamin B6, is a coenzyme involved in many enzymatic reactions.
T29033	U-7524	2-Aminooxyacetic acid,U 7524,Aminooxyacetic acid,U7524,AOAA
	U-7524, also known as AOAA and Aminooxyacetic acid, is an inhibitor of 4-aminobutyrate aminotransferase (GABA-T). AOAA is also a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (this includes GABA-T). It...
T73614	Tyrosine decarboxylase
	Tyrosine decarboxylase (TDC; TyrDC), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the decarboxylation of tyrosine, leading to the production of tyramine and carbon dioxide. This enzyme is prevalent in plant...
T82020	J5 peptide	Myelin basic protein (85-99) antagonist
	J5 peptide, an MBP inhibitor, competitively inhibits the binding of MBP 85-99 to HLA-DR2, and mitigates PLP 139-151/MBP 85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. It is utilized in research pe...
T71174	PBT434 HBr
	PBT434 is a novel, brain-penetrant, small molecule inhibitor of α-synuclein aggregation. In transgenic animal models of Parkinson disease (A53T) and MSA (PLP-α-Syn), PBT434 reduced α-synuclein aggregation, preserved neur...
T79929	L-Methionine γ-lyase	Methionine lyase
	L-Methionine γ-lyase (Methionine lyase), a multifaceted enzyme in the γ-family of pyridoxal-5’-phosphate (PLP)-dependent enzymes, catalyzes the α, γ-elimination of L-methionine and homocysteine. This enzyme exhibits anti...

Compounds

[SER140]-PLP(139-151) acetate

TP1312L

Synonym: [SER140]-PLP(139-151) acetate (122018-58-0 Free base)

Target: Others

PLP (139-151)

TP1282

Synonym: PLP 139-151

Target:

[SER140]-PLP(139-151) TFA (122018-58-0 free base)

TP1402

Synonym: [SER140]-PLP(139-151) TFA

Target:

[SER140]-PLP(139-151)

Plp(139-151) trifluoroacetate

T64674

Synonym:

Target:

[Leu144, Arg147]-PLP (139-151) TFA

T83690

Synonym: [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

Pyridoxal calcium phosphate

Synonym: 2-Aminooxyacetic acid,U 7524,Aminooxyacetic acid,U7524,AOAA

Target:

Tyrosine decarboxylase

Synonym: Myelin basic protein (85-99) antagonist

Synonym: Methionine lyase

Target:

Cat No.	Product Name	Synonyms	Targets
T3578	Pyridoxal phosphate	PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase , Endogenous Metabolite
	Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...		Reverse Transcriptase , Endogenous Metabolite
T5085	Pyridoxal 5'-phosphate hydrate	Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate	Others , Endogenous Metabolite
	Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth...		Others , Endogenous Metabolite
T8083	Pyridoxal 5'-phosphate monohydrate	Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate	Others
	Pyridoxal 5'-phosphate monohydrate is an active vitamin B6 metabolite		Others

Natural Products

Pyridoxal phosphate

T3578

Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Pyridoxal 5'-phosphate hydrate

T5085

Synonym: Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate

Target: Others, Endogenous Metabolite

Pyridoxal 5'-phosphate monohydrate

T8083

Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00082	PLP-C beta Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PLP-C beta Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is A0A0M6L0Y1.
TMPY-06767	Complement C3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_033908.2.
TMPY-02208	Peroxiredoxin 5 Protein, Human, Recombinant (His)	Human	E. coli
	Peroxiredoxin 5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.5 kDa and the accession number is P30044-2.
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPH-00865	RPLP0 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Ribosomal protein P0 is the functional equivalent of E.coli protein L10. RPLP0 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 5...
TMPH-02483	RPLP0 Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Ribosomal protein P0 is the functional equivalent of E.coli protein L10. RPLP0 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10XHis-SUMO and C-Myc tag. The predicted mole...
TMPY-04894	SARS-CoV (strain WH20) Plpro/papain-like protease (His)	SARS	E. coli
	SARS-CoV (strain WH20) Plpro/papain-like protease (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.65 kDa and the accession number is AAX16193.1.
TMPY-03628	APLP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1.
TMPK-00935	APLP2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0....
TMPY-05682	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Plpro/papain-like protease Protein (aa 1564-1880, His) is expressed in E. coli expression system. The predicted molecular weight is 36.79 kDa and the accession number is QVD65746.1.
TMPK-01352	SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi)	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPY-05356	RPLP1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	RPLP1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is A0A024R608.
TMPH-01722	PLP1 Protein, Human, Recombinant (His)	Human	E. coli
	This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. PLP1 Protein, Human, Recombinant (His) is expressed i...
TMPK-01384	SARS PLpro/papain-like protease Protein (His)	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro ...
TMPY-04693	APLP1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157.
TMPH-02870	PDXP Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP an...