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Cat No. | Product Name | Synonyms | Targets |
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T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T62338 | IMPDH2-IN-2 | ||
IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent. IMPDH2-IN-2 has a moderate antibacterial effect with MIC values of 6.3 and 11 μ... | |||
T0245 | RS 61443 | RS61443,Mycophenolate mofetil,TM-MMF | Dehydrogenase |
RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) | |||
T3444 | Merimepodib | VX-497,VI-21497 | Dehydrogenase , Antiviral , HCV Protease , HBV |
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH). | |||
T40686 | Tiazofurin | NSC 286193,Riboxamide | Dehydrogenase |
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) in... | |||
T22869 | Inosine-5'-monophosphate (sodium salt hydrate) | Others | |
substrate of IMP dehydrogenase (IMPDH) | |||
T23971 | DDD00079282 | DDD79282,DDD-79282,DDD-00079282,DDD 00079282,DDD 79282 | |
DDD00079282 is an inhibitor of IMPDH. | |||
T24691 | Q151 | Q-151,Q 151 | |
Q151 is an IMPDH inhibitor. It also is a potential antituberculosis agent. | |||
T24933 | VCC234718 | VCC-234718,VCC 234718 | |
VCC234718 is an IMPDH inhibitor. VCC234718 showed growth inhibitory activity against Mycobacterium tuberculosis. VCC234718 inhibits Mtb GuaB2 (Ki: 100 nM). | |||
T61099 | Mycophenolic acid sodium | ||
Mycophenolic acid sodium is a potent uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), exhibiting an EC50 of 0.24 μM. It has broad antiviral activity against RNA viruses, including influenza. Additi... | |||
T40447 | T-705RMP | ||
T-705RMP, the phosphorylated metabolite derived from T-705, demonstrates a limited inhibitory impact on the host cells' IMP dehydrogenase (IMPDH) activities, with an IC 50 value of 601 μM. | |||
T63246 | BMS-566419 | ||
BMS-566419 is an acridinone-based inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), a key enzyme for the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility in the study of graft reject... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1335 | Mycophenolic acid | Mycophenolate,RS-61443 | Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal |
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. | |||
T1188 | Mizoribine | Bredinin,NSC 289637,HE 69 | HCV Protease , SARS-CoV , Tyrosinase |
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. | |||
T6293 | Mycophenolate Mofetil | TM-MMF,RS 61443 | Apoptosis , Dehydrogenase , Drug Metabolite |
Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH). | |||
T4685 | INOSINIC ACID | Inosine 5′-monophosphate,IMP,I-5'-P | Endogenous Metabolite |
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03617 | GMPR Protein, Human, Recombinant (His) | Human | E. coli |
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme ... |