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Search Results for " impdh "

Targets

12

Compounds

4

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1979 AVN-944 VX-944 Dehydrogenase
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T62338 IMPDH2-IN-2
IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent. IMPDH2-IN-2 has a moderate antibacterial effect with MIC values of 6.3 and 11 μ...
T0245 RS 61443 RS61443,Mycophenolate mofetil,TM-MMF Dehydrogenase
RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)
T3444 Merimepodib VX-497,VI-21497 Dehydrogenase , Antiviral , HCV Protease , HBV
Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).
T40686 Tiazofurin NSC 286193,Riboxamide Dehydrogenase
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) in...
T22869 Inosine-5'-monophosphate (sodium salt hydrate) Others
substrate of IMP dehydrogenase (IMPDH)
T23971 DDD00079282 DDD79282,DDD-79282,DDD-00079282,DDD 00079282,DDD 79282
DDD00079282 is an inhibitor of IMPDH.
T24691 Q151 Q-151,Q 151
Q151 is an IMPDH inhibitor. It also is a potential antituberculosis agent.
T24933 VCC234718 VCC-234718,VCC 234718
VCC234718 is an IMPDH inhibitor. VCC234718 showed growth inhibitory activity against Mycobacterium tuberculosis. VCC234718 inhibits Mtb GuaB2 (Ki: 100 nM).
T61099 Mycophenolic acid sodium
Mycophenolic acid sodium is a potent uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), exhibiting an EC50 of 0.24 μM. It has broad antiviral activity against RNA viruses, including influenza. Additi...
T40447 T-705RMP
T-705RMP, the phosphorylated metabolite derived from T-705, demonstrates a limited inhibitory impact on the host cells' IMP dehydrogenase (IMPDH) activities, with an IC 50 value of 601 μM.
T63246 BMS-566419
BMS-566419 is an acridinone-based inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), a key enzyme for the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility in the study of graft reject...
Cat No. Product Name Synonyms Targets
T1335 Mycophenolic acid Mycophenolate,RS-61443 Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
T1188 Mizoribine Bredinin,NSC 289637,HE 69 HCV Protease , SARS-CoV , Tyrosinase
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
T6293 Mycophenolate Mofetil TM-MMF,RS 61443 Apoptosis , Dehydrogenase , Drug Metabolite
Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
T4685 INOSINIC ACID Inosine 5′-monophosphate,IMP,I-5'-P Endogenous Metabolite
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03617 GMPR Protein, Human, Recombinant (His) Human E. coli
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme ...
TargetMol