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Home > Neuroscience > BACE > Auraptene
Catalog No. T4115    CAS 495-02-3
Pack Size
In stock
1 mL * 10 mM (in DMSO)
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.17% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer’s disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.

Research Area:
Chemical Information:
Molecular Weight 298.4
Formula C19H22O3
CAS Number 495-02-3
Solubility DMSO:>20 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
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  • The compound is not included in our libraries at this moment.
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