Auraptene - Targetmol

Auraptene

Catalog No. T4115 CAS 495-02-3

Pack Size	Availability	Price/USD
1mg	In stock	87.00
1 mL * 10 mM (in DMSO)	Inquiry	50.00
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Documents and Quality Management

Purity：99.17%

COA

Datasheet

HNMR

HPLC

Biological Activity:

Product Description:

Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer’s disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.

Target:
BACE1;

Research Area:
Others

Chemical Information:

Molecular Weight	298.4
Formula	C₁₉H₂₂O₃
CAS Number	495-02-3
Solubility	DMSO:>20 mg/mL
Storage	3 years -20°C powder; 2 years -80°C in solvent;
Remark	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.

Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries

This product is contained In the following compound libraries：

The compound is not included in our libraries at this moment.

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Reference

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