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Steroids

Steroids

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes which alter membrane fluidity; and as signaling molecules. Hundreds of steroids are found in plants, animals and fungi.

Cat No. product name
T5S0246 Pseudoprotodioscin 1. Pseudoprotodioscin has moderate cytotoxicity.
TN1195 17-Hydroxy sprengerinin C 17-Hydroxy sprengerinin C is a natural product
TN2254 Taccalonolide A Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
TN2256 Taccalonolide B Taccalonolide B displays microtubule stabilizing activity.Several taccalonolides have in vitro antitrypanosomal activity against Trypanosoma brucei brucei and EC...
T2721 Digitonin Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.
TN2016 Ophiopogonin A Ophiopogonin A is a natural product
TN1102 Physalin L Physalin L shows a distinct fluorescence spot under UV 365 nm with good separation.
TN2052 Periplocoside M Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng/L),Hela( IC 50=8.63 ng/L) and MCF-7( IC 50=18.5 ng/L) cancer cell lines....
TN2349 Taurodeoxycholate sodium salt Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. T...
T5072 Glycocholic acid hydrate Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals.
TN1230 27-O-acetyl-withaferin A 27-O-acetyl-withaferin A is a natural product
TN2007 OJV-VI OJV-VI is a natural product
TN1201 (1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside (1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside is a natural product
TN2055 4)-beta-sarmentopyranoside]'>Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] is a natural product from Periploca sepiumBge.
T2733 Sarsasapogenin Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing pl...
T5S1982 Periplocin 1. Periplocin has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. ...
TN2255 Taccalonolide AJ Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that ...
TN1152 Anemarsaponin E Anemarsaponin E is a nartural product from salt Anemarrhenae Rhizoma.
T3394 Timosaponin BII Timosaponin BII has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-r...
T7030 Anemarsaponin B Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity...
T3874 Diosgenin glucoside Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significa...
TN1383 Anemarsaponin BIII Anemarsaponin BIII is a natural product
TN1327 7,22,25-Stigmastatrienol 7,22,25-Stigmastatrienol is a natural product
T0851 Pregnenolone Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer’s disease.
T2748 Cortodoxone Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
TN1382 Anemarrhenasaponin III Anemarrhenasaponin III is a natural product
T5254 Glycodeoxycholic acid sodium salt Glycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the ...
T5259 Glycochenodeoxycholic acid sodium salt Glycochenodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the mi...
TN1459 Bufarenogin Bufarenogin has inhibitory activity on human kidney Na(+)/K(+)-ATPase, it has cytotoxicity against HepG2 and MCF-7 human cancer cells.
TQ0065 Pseudobufarenogin Pseudobufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.
T3870 Cyasterone Cyasterone, a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer a...
TN1205 2,3-Didehydrosomnifericin 2,3-Didehydrosomnifericin is a natural product
TN1850 Lanatoside B Lanatoside B is a natural product from Polygonum lapathifolium.
T8184 Fucosterol Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and...
T2758 Madecassic acid Madecassic acid is extracted from the whole herb of Centella asiatica.
TN2274 Timorsaponin C Timorsaponin C is a natural product
T6473 Dioscin Dioscin is a saponin with antitumor activities.
T5S1252 Prosapogenin A Anticancer.
T3774 Gracillin Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can...
T6S1842 Tenacissoside G
T6S1843 Tenacissoside I Tenacissosides B, C, I and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.
T6S1844 Tenacissoside H Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
TN1617 Ergosta-4,6,8(14),22-tetraen-3-one Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatoce...
TN2266 Terrestrosin K Terrestrosin K is a natural product
TN1216 2-O-Acetyl-20-hydroxyecdysone 2-O-Acetyl-20-hydroxyecdysone is a natural product
TN1228 25S-Inokosterone 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2...
TN1227 25R-Inokosterone 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2...
TN2238 Stigmasterol glucoside Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.
TN1339 7beta-Hydroxybufalin 7beta-Hydroxybufalin is a natural product
TN2142 Resibufagin Resibufagin shows strong cytotoxic activity against HeLa cell line.
T4717 25-Hydroxycholesterol 25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase...
TN1364 Ajugasterone C Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats...
TN2063 Physalin B Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemothera...
TN1199 19-Oxocinobufagin 19-Oxocinobufagin is a natural product from Bufo bufo gargarizans Cantor.
TN1200 19-Oxocinobufotalin 19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.
T3S0237 Precyasterone
T5239 Cholesterol 3-Sulfate Sodium Salt Cholesterol sulfate is a sterol sulfate in human plasma. It is a component of cell membrane and has a regulatory function. It also activates multiple protein kin...
T3220 Euphorbiasteroid Euphorbiasteroid (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.
TN1399 Arenobufagin 3-hemisuberate Arenobufagin 3-hemisuberate is a natural product
T5077 Sodium Desoxycholate Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
TN2054 Periplocymarin Periplocymarin, a cardiac glycoside, has potential anti-cancer activity.
TN2309 Withanolide A Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans.
TN1075 Adynerin Standard reference
T5352 GLYCODEOXYCHOLIC ACID Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
T2220 2-Methoxyestradiol 2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
T2207 Adrenosterone Adrenosterone is a steroid hormone isolated from the adrenal cortex.
T3150 Caudatin Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.
TN1198 19-Hydroxybufalin 19-Hydroxybufalin is a natural product
TN2053 Periplocoside N Periplocoside N possesses insecticidal activities against the red imported fire ant.
TQ0170 Desacetylcinobufagin Deacetylcinobufagin, a natural product, shows potent activities against Hela and A375 cells in vitro.
TN1572 Desacetylcinobufotalin Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against...
T3395 Timosaponin AIII Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10μM). The Timosaponin AIII cellular response is mediated via inhibitio...
TN2287 Turkesterone Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodul...
T2202 Lithocholic acid Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubili...
T4923 7-Dehydrocholesterol 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
T0799 Lactulose Lactulose ,a synthetic disaccharide ,is used in the treatment of constipation and hepatic encephalopathy.
T5A2455 Arenobufagin Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/A...
T2827 Asiatic acid Asiatic acid is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.
T4A2456 Gamabufotalin 1. Gamabufotalin , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stab...
T5S0890 Oleandrin 1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
T1719 Bufalin Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from t...
TN2105 Proscillaridin A Proscillaridin A is a natural product
T4878 Hecogenin Hecogenin is a steroid saponin isolated from Agave sisalana. It is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of ...
T3432 Cinobufagin Cinobufagin is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
TN1912 Marinobufagenin Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
T5A2461 Bufotaline 1. Bufotaline is a kind of poisonous secretions of toads.
T6S1256 Ruscogenin 1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner,2. Ruscogenin i...
T4A2462 Telocinobufagin 1. Telocinobufagin is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the...
T0847 Chenodeoxycholic acid Chenodiol is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbe...
T3871 Sitogluside Eleutheroside A (Daucosterol) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol has efficient and inexpensive neuroprote...
TN1450 Brassicasterol Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).
T2831 Glycocholic acid Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
TN1377 Alpha-Spinasterol Alpha-Spinasterol is a novel efficacious and safe antagonist of the TRPV1 receptor with anti-inflammatory and antinociceptive effects.
T2195 Epiandrosterone Epiandrosterone is a dehydroepiandrosterone metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic property.
T1614 Hydrocortisone Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppr...
T1571 Estriol Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
T1048 Estradiol Estradiol is an Estrogen. The mechanism of action of estradiol is as an Estrogen Receptor Agonist.
T3895 Polyphyllin I Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, c...
TN1525 Convallatoxin Convallatoxin is a natural product
TN1729 Hellebrigenol Hellebrigenol shows cytotoxicity against HepG2 cells.
Pseudoprotodioscin
T5S0246CAS 102115-79-7
1. Pseudoprotodioscin has moderate cytotoxicity.
17-Hydroxy sprengerinin C
TN1195CAS 1029017-75-1
17-Hydroxy sprengerinin C is a natural product
Taccalonolide A
TN2254CAS 108885-68-3
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
Taccalonolide B
TN2256CAS 108885-69-4
Taccalonolide B displays microtubule stabilizing activity.Several taccalonolides have in vitro antitrypanosomal activity against Trypanosoma brucei brucei and EC...
Digitonin
T2721CAS 11024-24-1
Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth.
Ophiopogonin A
TN2016CAS 11054-24-3
Ophiopogonin A is a natural product
Physalin L
TN1102CAS 113146-74-0
Physalin L shows a distinct fluorescence spot under UV 365 nm with good separation.
Periplocoside M
TN2052CAS 116782-73-1
Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng/L),Hela( IC 50=8.63 ng/L) and MCF-7( IC 50=18.5 ng/L) cancer cell lines....
Taurodeoxycholate sodium salt
TN2349CAS 1180-95-6
Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. T...
Glycocholic acid hydrate
T5072CAS 1192657-83-2
Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals.
27-O-acetyl-withaferin A
TN1230CAS 1214886-35-7
27-O-acetyl-withaferin A is a natural product
OJV-VI
TN2007CAS 125150-67-6
OJV-VI is a natural product
(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside
TN1201CAS 125225-63-0
(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside is a natural product
4)-beta-sarmentopyranoside]'>Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside]
TN2055CAS 1253421-94-1
Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside] is a natural product from Periploca sepiumBge.
Sarsasapogenin
T2733CAS 126-19-2
Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing pl...
Periplocin
T5S1982CAS 13137-64-9
1. Periplocin has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. ...
Taccalonolide AJ
TN2255CAS 1349904-82-0
Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that ...
Anemarsaponin E
TN1152CAS 136565-73-6
Anemarsaponin E is a nartural product from salt Anemarrhenae Rhizoma.
Timosaponin BII
T3394CAS 136656-07-0
Timosaponin BII has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-r...
anemarsaponin B
T7030CAS 139051-27-7
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity...
Diosgenin glucoside
T3874CAS 14144-06-0
Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significa...
Anemarsaponin BIII
TN1383CAS 142759-74-8
Anemarsaponin BIII is a natural product
7,22,25-Stigmastatrienol
TN1327CAS 14485-48-4
7,22,25-Stigmastatrienol is a natural product
Pregnenolone
T0851CAS 145-13-1
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer’s disease.
Cortodoxone
T2748CAS 152-58-9
Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
Anemarrhenasaponin III
TN1382CAS 163047-23-2
Anemarrhenasaponin III is a natural product
Glycodeoxycholic acid sodium salt
T5254CAS 16409-34-0
Glycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the ...
Glycochenodeoxycholic acid sodium salt
T5259CAS 16564-43-5
Glycochenodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the mi...
Bufarenogin
TN1459CAS 17008-65-0
Bufarenogin has inhibitory activity on human kidney Na(+)/K(+)-ATPase, it has cytotoxicity against HepG2 and MCF-7 human cancer cells.
Pseudobufarenogin
TQ0065CAS 17008-69-4
Pseudobufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling.
Cyasterone
T3870CAS 17086-76-9
Cyasterone, a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer a...
2,3-Didehydrosomnifericin
TN1205CAS 173614-88-5
2,3-Didehydrosomnifericin is a natural product
Lanatoside B
TN1850CAS 17575-21-2
Lanatoside B is a natural product from Polygonum lapathifolium.
Fucosterol
T8184CAS 17605-67-3
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and...
Madecassic acid
T2758CAS 18449-41-7
Madecassic acid is extracted from the whole herb of Centella asiatica.
Timorsaponin C
TN2274CAS 185432-00-2
Timorsaponin C is a natural product
Dioscin
T6473CAS 19057-60-4
Dioscin is a saponin with antitumor activities.
Prosapogenin A
T5S1252CAS 19057-67-1
Anticancer.
Gracillin
T3774CAS 19083-00-2
Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can...
Tenacissoside G
T6S1842CAS 191729-43-8
Tenacissoside I
T6S1843CAS 191729-44-9
Tenacissosides B, C, I and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.
Tenacissoside H
T6S1844CAS 191729-45-0
Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
Ergosta-4,6,8(14),22-tetraen-3-one
TN1617CAS 19254-69-4
Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatoce...
Terrestrosin K
TN2266CAS 193605-07-1
Terrestrosin K is a natural product
2-O-Acetyl-20-hydroxyecdysone
TN1216CAS 19536-25-5
2-O-Acetyl-20-hydroxyecdysone is a natural product
25S-Inokosterone
TN1228CAS 19595-18-7
25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2...
25R-Inokosterone
TN1227CAS 19682-38-3
25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2...
Stigmasterol glucoside
TN2238CAS 19716-26-8
Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.
7beta-Hydroxybufalin
TN1339CAS 20143-97-9
7beta-Hydroxybufalin is a natural product
Resibufagin
TN2142CAS 20987-24-0
Resibufagin shows strong cytotoxic activity against HeLa cell line.
25-Hydroxycholesterol
T4717CAS 2140-46-7
25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase...
Ajugasterone C
TN1364CAS 23044-80-6
Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats...
Physalin B
TN2063CAS 23133-56-4
Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemothera...
19-Oxocinobufagin
TN1199CAS 24512-59-2
19-Oxocinobufagin is a natural product from Bufo bufo gargarizans Cantor.
19-Oxocinobufotalin
TN1200CAS 24512-60-5
19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.
Precyasterone
T3S0237CAS 27335-85-9
Cholesterol 3-Sulfate Sodium Salt
T5239CAS 2864-50-8
Cholesterol sulfate is a sterol sulfate in human plasma. It is a component of cell membrane and has a regulatory function. It also activates multiple protein kin...
Euphorbiasteroid
T3220CAS 28649-59-4
Euphorbiasteroid (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.
Arenobufagin 3-hemisuberate
TN1399CAS 30219-16-0
Arenobufagin 3-hemisuberate is a natural product
Sodium Desoxycholate
T5077CAS 302-95-4
Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
Periplocymarin
TN2054CAS 32476-67-8
Periplocymarin, a cardiac glycoside, has potential anti-cancer activity.
Withanolide A
TN2309CAS 32911-62-9
Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans.
Adynerin
TN1075CAS 35109-93-4
Standard reference
GLYCODEOXYCHOLIC ACID
T5352CAS 360-65-6
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
2-Methoxyestradiol
T2220CAS 362-07-2
2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
Adrenosterone
T2207CAS 382-45-6
Adrenosterone is a steroid hormone isolated from the adrenal cortex.
Caudatin
T3150CAS 38395-02-7
Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.
19-Hydroxybufalin
TN1198CAS 39844-86-5
19-Hydroxybufalin is a natural product
Periplocoside N
TN2053CAS 39946-41-3
Periplocoside N possesses insecticidal activities against the red imported fire ant.
Desacetylcinobufagin
TQ0170CAS 4026-95-3
Deacetylcinobufagin, a natural product, shows potent activities against Hela and A375 cells in vitro.
Desacetylcinobufotalin
TN1572CAS 4099-30-3
Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against...
Timosaponin AIII
T3395CAS 41059-79-4
Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10μM). The Timosaponin AIII cellular response is mediated via inhibitio...
Turkesterone
TN2287CAS 41451-87-0
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodul...
Lithocholic acid
T2202CAS 434-13-9
Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubili...
7-Dehydrocholesterol
T4923CAS 434-16-2
7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
Lactulose
T0799CAS 4618-18-2
Lactulose ,a synthetic disaccharide ,is used in the treatment of constipation and hepatic encephalopathy.
Arenobufagin
T5A2455CAS 464-74-4
Arenobufagin is a natural bufadienolide from toad venom with potent antineoplastic activity against HCC HepG2 cells and corresponding multidrug-resistant HepG2/A...
Asiatic acid
T2827CAS 464-92-6
Asiatic acid is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.
Gamabufotalin
T4A2456CAS 465-11-2
1. Gamabufotalin , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stab...
Oleandrin
T5S0890CAS 465-16-7
1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional lev...
Bufalin
T1719CAS 465-21-4
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from t...
Proscillaridin A
TN2105CAS 466-06-8
Proscillaridin A is a natural product
Hecogenin
T4878CAS 467-55-0
Hecogenin is a steroid saponin isolated from Agave sisalana. It is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of ...
Cinobufagin
T3432CAS 470-37-1
Cinobufagin is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
Marinobufagenin
TN1912CAS 470-42-8
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
Bufotaline
T5A2461CAS 471-95-4
1. Bufotaline is a kind of poisonous secretions of toads.
Ruscogenin
T6S1256CAS 472-11-7
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner,2. Ruscogenin i...
Telocinobufagin
T4A2462CAS 472-26-4
1. Telocinobufagin is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the...
Chenodeoxycholic acid
T0847CAS 474-25-9
Chenodiol is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbe...
Sitogluside
T3871CAS 474-58-8
Eleutheroside A (Daucosterol) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol has efficient and inexpensive neuroprote...
Brassicasterol
TN1450CAS 474-67-9
Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).
Glycocholic acid
T2831CAS 475-31-0
Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
alpha-Spinasterol
TN1377CAS 481-18-5
Alpha-Spinasterol is a novel efficacious and safe antagonist of the TRPV1 receptor with anti-inflammatory and antinociceptive effects.
Epiandrosterone
T2195CAS 481-29-8
Epiandrosterone is a dehydroepiandrosterone metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic property.
Hydrocortisone
T1614CAS 50-23-7
Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppr...
Estriol
T1571CAS 50-27-1
Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
Estradiol
T1048CAS 50-28-2
Estradiol is an Estrogen. The mechanism of action of estradiol is as an Estrogen Receptor Agonist.
Polyphyllin I
T3895CAS 50773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, c...
Convallatoxin
TN1525CAS 508-75-8
Convallatoxin is a natural product
Hellebrigenol
TN1729CAS 508-79-2
Hellebrigenol shows cytotoxicity against HepG2 cells.
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