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ly487379

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LY487379
T62756353231-17-1
LY487379 is a selective human mGluR2 positive allosteric modulator (PAM) that enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 μM) and mGlu3 receptors (EC50 >10 μM). LY487379 induces cognitive flexibility and behavioral inhibition in a rat model and can be used to study schizophrenia.
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7-10 days
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LY487379 hydrochloride
LY 487379 hydrochloride
T22955353229-59-1
Positive allosteric modulator of mGlu2 receptors
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6-8 weeks
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