nnrti — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7700	Lersivirine	Lersivirine(UK 453061),UK-453061	HIV Protease , Reverse Transcriptase
	Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.		HIV Protease , Reverse Transcriptase
T7212	Delavirdine mesylate	U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease , Reverse Transcriptase
	Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).		HIV Protease , Reverse Transcriptase
T2330	Rilpivirine	TMC278,R278474,DB08864	HIV Protease , Reverse Transcriptase
	Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections.		HIV Protease , Reverse Transcriptase
T78948	NNRTIs-IN-1
	NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type HIV-1 and five mutant strains at EC50 values within the nano...
T78737	NNRTIs-IN-3		HIV Protease
	NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 µM [1].		HIV Protease
T31860	Fosdevirine	GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A	HIV Protease
	Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.		HIV Protease
T31860L	(Iso)-Fosdevirine	(Iso)-Fosdevirine（Iso-1018450-26-4）,(Iso)-GSK2248761	HIV Protease
	(Iso)-Fosdevirine ( (Iso)-GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological disorders such as late-onset epilepsy.		HIV Protease
T9223	RO-0335		Reverse Transcriptase
	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is...		Reverse Transcriptase
T29037	UC-781	NSC 675186,UC781,UC 781	Antiviral , HIV Protease
	UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resis...		Antiviral , HIV Protease
T27625	IQP-0528	SJ-3991,SJ3991,IQP0528	Antiviral , HIV Protease , Reverse Transcriptase
	IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and shows antiviral activity as a microbicidal gel. . IQP-0528 sho...		Antiviral , HIV Protease , Reverse Transcriptase
T71517	Nevirapine quinone methide
	Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
T31085	CP-94707	UNII-YGC6408B5O
	CP-94707 is a new inhibitor of nonnucleoside reverse transcriptase (NNRTI).
T26442	A 75925	A-75925,A75925
	A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.
T70794	Nevirapine dimer
	Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
T72582	HIV-1 inhibitor-48
	HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity .
T70156	K-5a2
	K-5a2 is a novel human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor (NNRTI).
T69796	Nevirapine hemihydrate
	Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS.
T27442	GSK 224876	GSK-224876,GSK224876
	GSK 224876 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). It has activity against efavirenz-resistant strains in the treatment of treatment-naive HIV-1-infected subjects.
T11247	Etravirine D4	R-165335 D4,TMC-125 D4	Others
	Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.		Others
T7212L	Delavirdine	Rescriptor,DLV,U 90152,BHAP-U 90152
	Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine is part of Highly Active Antiretroviral Therapy (HAART), which can be used to treat human immunodeficiency virus (HIV) type 1.
T79837	Bavtavirine
	Bavtavirine, a potent non-nucleoside reverse transcriptase inhibitor (NNRTI), forms an integral component of the highly active antiretroviral therapy (HAART) regimen for HIV disease research [1].
T63677	HIV-1 inhibitor-13
	HIV-1 inhibitor-13 is an orally active HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with an IC50 value of 0.14 μM against HIV-1 RT. HIV-1 inhibitor-13 is active against HIV-1 resistant strains (EC50: 2.85...
T62452	HIV-1 inhibitor-40
	HIV-1 inhibitor-40 (Compound 4ab) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) (EC50: 1.9 nM) with no significant acute toxicity in vivo. Orexin receptor antagonist is a highly sensitive inhibitor o...
T72566	HIV-1 inhibitor-50
	HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM a...
T63363	HIV-1 inhibitor-19
	HIV-1 inhibitor-19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRTI) that acts on L100I, K103N and V106A/F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively.
T74516	CI-39
	CI-39, a natural antiviral product, serves as a non-nucleoside reverse transcriptase inhibitor (NNRTI) targeting wild type HIV-1. It exhibits an effective concentration (EC50) of 3.40 µM against the virus, while its cyto...
T78749	HIV-1 inhibitor-57
	HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficac...
T62526	HIV-1 inhibitor-8
	HIV-1 inhibitor-8 is a potent, orally active, low toxicity HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 is capable of acting on WT HIV-1 reverse transcriptase (IC50: 0.081 μM). HIV-1 in...
T26581	AIC-292
	AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained ...
T78925	HIV-1 inhibitor-58
	HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138...
T61311	HIV-1 inhibitor-30
	HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM....