mdp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16159	Muramyl dipeptide	MDP	NOD
	Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...		NOD
T74731	L18-MDP
	L18-MDP, a derivative of the antibacterial agent muramyl dipeptide, exhibits antibacterial activity and shows promise for use in treating bacterial and fungal infections [1].
TP2405	Romurtide	MDP-lys(L18),CCRIS 1220,DJ-7041,Nopia
	Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T13856	(R)-DNMDP		Others
	(R)-DNMDP is a potent and selective agent of cancer cell cytotoxic.		Others
T76219	MDP1
	MDP1, derived from Melittin, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria, leading to bacterial death through membrane damage. This compound exhibits potent antibacterial activity agai...
T37804	8MDP
	Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluat...
T15147	DNMDP		Others
	DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12.		Others
T18333	mDPR(Boc)-Val-Cit-PAB		Others
	mDPR(Boc)-Val-Cit-PAB is a cleavable linker employed in antibody-drug conjugates (ADCs) [1]. This chemical compound serves as a reliable linker in the formation of ADCs, which are biopharmaceuticals that combine the spec...		Others
T67428	mDPR-Val-Cit-PAB-MMAE
	mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate.
T28007	MDPD
	MDPD is an enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis. MDPD alleviates the growth inhibitory effects of NAE 12:0, in part by enhancing the enzymatic activity of Arabid...
T76219L	MDP1 acetate
	MDP1 acetate, a derivative of Melittin, compromises the membrane integrity of both Gram-positive and Gram-negative bacteria leading to bacterial death through membrane damage. It exhibits potent antibacterial activity ag...
T27344	FMDP
	FMDP is a glucosamine-6-phosphate synthase inhibitor.
T79600	Zharp2-1		RIP kinase
	Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ...		RIP kinase
T77644	AJ2-30		Others
	AJ2-30 is an SLCl5A4 inhibitor that inhibits TLR9-mediated B cell activation and inhibits MDP transporter.AJ2-30 inhibits endogenous NOD signaling in human and mouse macrophages.AJ2-30 can be used for the study of inflam...		Others
T63088	NOD2 antagonist 1
	NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23μM). NOD2 antagonist 1 in THP-1 cells repress Muramyl DiDP (MDP) -induced IL-8 secretion. NOD2 antagonist 1 in PBMCs cells inhibits...
T77782	MOTS-c
	MOTS-c is a mitochondria-derived polypeptide (MDP) that has anti-damage and anti-inflammatory effects by activating the AMPK pathway and inhibiting the MAP kinase-c-fos signaling pathway.
T83152	AJ2-71
	AJ2-71 is a SLC15A4 inhibitor that suppresses IFN-α production and obstructs SLC15A4-mediated MDP transport, making it suitable for research of inflammation [1].
T73862	Almurtide
	Almurtide (nor-MDP), a derivative of muramyl dipeptide, exhibits anti-inflammatory and anti-tumor properties. It demonstrates protective effects in mice against infections caused by Pseudomonas aeruginosa when administer...
T74089	Mifamurtide TFA
	Mifamurtide TFA (MTP-PE TFA), a muramyl dipeptide (MDP) analog, acts as a nonspecific immunomodulator by activating macrophages and monocytes to stimulate the immune response. As an orphan agent and a specific NOD2 ligan...

Compounds

Muramyl dipeptide

T16159

Synonym: MDP-lys(L18),CCRIS 1220,DJ-7041,Nopia

Target: IL Receptor, NOD

mDPR(Boc)-Val-Cit-PAB

T18333

Synonym:

Target: Others

mDPR-Val-Cit-PAB-MMAE

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03329	DPEP1 Protein, Human, Recombinant (His)	Human	HEK293
	Dehydropeptidase-I, also known as DPEP1, is a kidney membrane enzyme. Its expression in normal colonic mucosa is very low, but it is highly expressed in colorectal adenoma and cancer specimens and is negatively correl...
TMPJ-01205	MDP1 Protein, Human, Recombinant (His)	Human	Human Cells
	MDP1, which is short for nesium-dependent phosphatase 1, is a 176 aa. protein. It has 3 forms by different alternative splicing. This protein belongs to the HAD-like hydrolase superfamily, and usually takes its function ...
TMPH-00289	NOD2 Protein, Bovine, Recombinant (His & KSI)	Bovine	E. coli
	Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, ...
TMPH-01738	NLRP1 Protein, Human, Recombinant (GST)	Human	E. coli
	Acts as the sensor component of the NLRP1 inflammasome, which mediates inflammasome activation in response to various pathogen-associated signals, leading to subsequent pyroptosis. Inflammasomes are supramolecular comple...