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OXPHOS

Oxidative phosphorylation or electron transport-linked phosphorylation or terminal oxidation is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing chemical energy in order to produce adenosine triphosphate (ATP). In eukaryotes, this takes place inside mitochondria. Almost all aerobic organisms carry out oxidative phosphorylation. This pathway is so pervasive because it releases more energy than alternative fermentation processes such as anaerobic glycolysis.

Acetyl Coenzyme A trisodium
T37958102029-73-2
Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle.
  • $56
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DX3-213B
T631362749555-66-4
DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM. DX3-213B blocks ATP production (IC50: 11 nM) and inhibits the growth of MIA PaCa-2 cells (GI50: 11 nM). DX3-213B can be used to study pancreatic cancer.
  • $74
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BAM 15
T14497210302-17-3
BAM 15 is an uncoupler of mitochondrial protonophore.
  • $59
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Mito-LND
T92112361564-49-8
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
  • $81
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IM156
T85321422365-93-2
IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model [1] [2]. IM156 is a potent oxidative phosphorylation (OXPHOS) inhibitor which is able to be used for the research of solid tumors [3].
  • $33
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TargetMol | Citations Cited
VLX600
T8500327031-55-0
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
  • $30
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