c-Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.

Cat. No.	Product name	CAS No.	Purity
TN4581	Moracin D	69120-07-6	98%
TN4581	Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
T10702	CBP/p300-IN-2	2158265-96-2	98%
T10702	CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
TN1354	Aaptamine	85547-22-4	98%
TN1354	Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T11783	KSI-3716	1151813-61-4	98%
T11783	KSI-3716 is an inhibitor of c-Myc.
T16839	SAJM589	2089-82-9	98%
T16839	sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
TN4582	Moracin T	1146113-27-0	98%
TN4582	Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
TN2177	Sanggenol L	329319-20-2	98%
TN2177	Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
TN3708	Coronarin D	119188-37-3	98%
TN3708	Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
T9628	10074-A4	312631-87-1	98%
T9628	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from th...
T15665	KJ Pyr 9	581073-80-5	98%
T15665	KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).
T3686	10074-G5	413611-93-5	98%
T3686	10074-G5 is an inhibitor of c-Myc-Max dimerization.
T12134	MYCMI-6	681282-09-7	98%
T12134	MYCMI-6 is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a...
T9061	EN4	1197824-15-9	98%
T9061	EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional ...
T4367	Mycro 3	944547-46-0	98%
T4367	Mycro 3 is potent and selective for c-Myc in whole cell assays.
TN1892	Lusianthridin	87530-30-1	98%
TN1892	Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-...
T12132	MYCi361	2289690-31-7	98%
T12132	MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
T12133	MYCi975	2289691-01-4	98%
T12133	MYCi975 is an orally active inhibitor of MYC.
T10352	APTO-253	916151-99-0	98%
T10352	APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates a...
T4252	ML327	1883510-31-3	98%
T4252	ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
T9093	NY2267	886053-73-2	98%
T9093	NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.