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Search Results for " dgtp "

Targets

15

Compounds

5

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T40192 dGTP 2'-Deoxyguanosine-5'-triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
T40671 7-Deaza-7-propargylamino-dGTP
7-Deaza-7-propargylamino-dGTP is an analogue of dGTP, specifically designed for the purpose of gene sequencing.
T40773 7-Deaza-7-propargylamino-3'-azidomethyl-dGTP
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is a commonly employed deoxyguanosine triphosphate (dGTP) analog in next generation sequencing (NGS).
T36688 Deoxyguanosine triphosphate trisodium salt Deoxyguanosine 5-triphosphate,2'-Deoxyguanosine-5'-triphosphate trisodium salt,dGTP trisodium salt Nucleoside Antimetabolite/Analog
Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (R...
T83247 7-Deaza-dGTP tetralithium
7-Deaza-dGTP tetralithium is utilized for the amplification of GC-rich DNA sequences [1].
T83810 3'-Amino-3'-deoxyguanosine-5'-O-triphosphate sodium 3'-amino-dGTP
3'-Amino-3'-deoxyguanosine-5'-O-triphosphate (3'-amino-dGTP), an amine-modified nucleotide, effectively terminates RNA strand synthesis as catalyzed by RNA polymerase in E. coli. This compound has also been utilized in c...
T83248 7-Deaza-2′-deoxyguanosine 5′-triphosphate 7-Deaza-2'-dGTP Telomerase
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].
T83831 Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) sodium Sp-dGTP-α-S
Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an ...
T38529 7-Deaza-7-propargylamino-ddGTP
7-Deaza-7-propargylamino-ddGTP is a gene sequencing analog of dideoxyguanosine triphosphate (ddGTP).
T40799 DdGTP 2′,3′-Dideoxyguanosine 5′-triphosphate,ddGTP
ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.
T74023 DdGTP trisodium
2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) trisodium, a member of the 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs), functions as a chain-elongating inhibitor of DNA polymerase, pivotal for DNA sequencing. It...
T15337 Forodesine BCX-1777,Immucillin-H Others
Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i...
T11313 Forodesine hydrochloride BCX-1777 hydrochloride,Immucillin-H hydrochloride Others
Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly...
T27260 Emivirine MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302 HIV Protease
Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.
T35652 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be effi...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00568 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorpora...
TMPH-00609 DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) E. coli E. coli
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinos...
TMPH-03195 Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) Pyrococcus horikoshii E. coli
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP s...
TMPJ-01429 SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) SARS-CoV-2 E. coli
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds...
TMPY-03508 XTP3TPA Protein, Human, Recombinant (His) Human E. coli
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-d...
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