15
5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40192 | dGTP | 2'-Deoxyguanosine-5'-triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. | |||
T40671 | 7-Deaza-7-propargylamino-dGTP | ||
7-Deaza-7-propargylamino-dGTP is an analogue of dGTP, specifically designed for the purpose of gene sequencing. | |||
T40773 | 7-Deaza-7-propargylamino-3'-azidomethyl-dGTP | ||
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is a commonly employed deoxyguanosine triphosphate (dGTP) analog in next generation sequencing (NGS). | |||
T36688 | Deoxyguanosine triphosphate trisodium salt | Deoxyguanosine 5-triphosphate,2'-Deoxyguanosine-5'-triphosphate trisodium salt,dGTP trisodium salt | Nucleoside Antimetabolite/Analog |
Deoxyguanosine triphosphate trisodium salt (2'-Deoxyguanosine-5'-triphosphate trisodium salt) is a nucleotide precursor for DNA synthesis in cells and can be used in the reverse transcription-polymerase chain reaction (R... | |||
T83247 | 7-Deaza-dGTP tetralithium | ||
7-Deaza-dGTP tetralithium is utilized for the amplification of GC-rich DNA sequences [1]. | |||
T83810 | 3'-Amino-3'-deoxyguanosine-5'-O-triphosphate sodium | 3'-amino-dGTP | |
3'-Amino-3'-deoxyguanosine-5'-O-triphosphate (3'-amino-dGTP), an amine-modified nucleotide, effectively terminates RNA strand synthesis as catalyzed by RNA polymerase in E. coli. This compound has also been utilized in c... | |||
T83248 | 7-Deaza-2′-deoxyguanosine 5′-triphosphate | 7-Deaza-2'-dGTP | Telomerase |
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1]. | |||
T83831 | Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) sodium | Sp-dGTP-α-S | |
Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an ... | |||
T38529 | 7-Deaza-7-propargylamino-ddGTP | ||
7-Deaza-7-propargylamino-ddGTP is a gene sequencing analog of dideoxyguanosine triphosphate (ddGTP). | |||
T40799 | DdGTP | 2′,3′-Dideoxyguanosine 5′-triphosphate,ddGTP | |
ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. | |||
T74023 | DdGTP trisodium | ||
2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) trisodium, a member of the 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs), functions as a chain-elongating inhibitor of DNA polymerase, pivotal for DNA sequencing. It... | |||
T15337 | Forodesine | BCX-1777,Immucillin-H | Others |
Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i... | |||
T11313 | Forodesine hydrochloride | BCX-1777 hydrochloride,Immucillin-H hydrochloride | Others |
Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly... | |||
T27260 | Emivirine | MKC442,MKC-442,MKC 442,DRG-0302,DRG 0302,DRG0302 | HIV Protease |
Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1. | |||
T35652 | 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) | ||
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be effi... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00568 | 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorpora... | |||
TMPH-00609 | DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinos... | |||
TMPH-03195 | Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc) | Pyrococcus horikoshii | E. coli |
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP s... | |||
TMPJ-01429 | SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) | SARS-CoV-2 | E. coli |
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds... | |||
TMPY-03508 | XTP3TPA Protein, Human, Recombinant (His) | Human | E. coli |
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-d... |