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Search Results for " casr "

Targets

24

Compounds

1

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T79023 CaSR antagonist-1 CaSR
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeosta...
T12846 SB-423562 CaSR
SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.
T15261 Evocalcet KHK7580 CaSR
Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).
T8457 NPS2390 GluR
NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)
T8403 Cinacalcet AMG 073 CaSR
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .
T22795 Gadolinium chloride CaSR
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist
T1641 Strontium ranelate Distrontium renelate,S12911 Calcium Channel , CaSR
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both in...
T2406 Cinacalcet hydrochloride AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet CaSR
Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces para...
TP1236 Etelcalcetide hydrochloride AMG 416 hydrochloride,KAI-4169 hydrochloride CaSR
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi...
T1730 NPS-2143 SB262470,NPS 2143,SB 262470A Calcium Channel , CaSR
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
T4967 NPS-2143 hydrochloride NPS-2143 HCL CaSR
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
T40363 Poly-D-lysine hydrobromide (MW 30000-70000) Poly-D-lysine HBr (MW 30000-70000) CaSR
Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.
T23401 Strontium chloride Others , CaSR
Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.
T7716 TNCA Lycoperodine-1 Others
TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.
T13918 Tecalcet Hydrochloride R-568 hydrochloride,R-568 (hydrochloride) CaSR
Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.
T34385 Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 CaSR
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
T29541 AC265347 AC-265347 CaSR
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud...
T10666 Calhex 231 hydrochloride CaSR
Calhex 231 hydrochloride is a CaSR inhibitor with the potential for diabetic cardiomyopathy treatment. It blocks Ca2+-induced accumulation of [3H]inositol phosphate (IC50: 0.39 μM in HEK293 cells).
T11493 GSK3004774 Others
GSK3004774 is a nonabsorbable agonist of CaSR (pEC50: 7.3, 6.6, and 6.5 for human, mouse, and rat CaSR). GSK3004774 shows an EC50 of 50 nM for human CaSR.
TP1235 Etelcalcetide AMG 416,KAI-4169
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodi...
T31624 Encaleret JIT305,JIT 305
Encaleret( JIT-305) is an antagonist of oral calcium-sensing receptor (CaSR), it is used for the treatment of osteoporosis.
T21758 Calindol (hydrochloride)
Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.
T72908 Gamma-Glu-Abu
Gamma-Glu-Abu is a potent calcium sensing receptor (CaSR) agonist .
T12845 SB-423557 Calcium Channel
SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM

Compounds

CaSR antagonist-1
T79023
Synonym:
Target: CaSR
SB-423562
T12846
Synonym:
Target: CaSR
Evocalcet
T15261
Synonym: KHK7580
Target: CaSR
NPS2390
T8457
Synonym:
Target: GluR
Cinacalcet
T8403
Synonym: AMG 073
Target: CaSR
Gadolinium chloride
T22795
Synonym:
Target: CaSR
Strontium ranelate
T1641
Synonym: Distrontium renelate,S12911
Target: Calcium Channel, CaSR
Cinacalcet hydrochloride
T2406
Synonym: AMG-073 HCl,Cinacalcet HCl,AMG-073 hydrochloride,Cinacalcet
Target: CaSR
Etelcalcetide hydrochloride
TP1236
Synonym: AMG 416 hydrochloride,KAI-4169 hydrochloride
Target: CaSR
NPS-2143
T1730
Synonym: SB262470,NPS 2143,SB 262470A
Target: Calcium Channel, CaSR
NPS-2143 hydrochloride
T4967
Synonym: NPS-2143 HCL
Target: CaSR
Poly-D-lysine hydrobromide (MW 30000-70000)
T40363
Synonym: Poly-D-lysine HBr (MW 30000-70000)
Target: CaSR
Strontium chloride
T23401
Synonym:
Target: Others, CaSR
TNCA
T7716
Synonym: Lycoperodine-1
Target: Others
Tecalcet Hydrochloride
T13918
Synonym: R-568 hydrochloride,R-568 (hydrochloride)
Target: CaSR
Ronacaleret HCl
T34385
Synonym: SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689
Target: CaSR
AC265347
T29541
Synonym: AC-265347
Target: CaSR
Calhex 231 hydrochloride
T10666
Synonym:
Target: CaSR
GSK3004774
T11493
Synonym:
Target: Others
Etelcalcetide
TP1235
Synonym: AMG 416,KAI-4169
Target:
Encaleret
T31624
Synonym: JIT305,JIT 305
Target:
Calindol (hydrochloride)
T21758
Synonym:
Target:
Gamma-Glu-Abu
T72908
Synonym:
Target:
SB-423557
T12845
Synonym:
Target: Calcium Channel
Cat No. Product Name Synonyms Targets
T3802 Ligustroflavone Nuezhenoside Others , CaSR
Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01315 CASR Protein, Human, Recombinant (GST) Human E. coli
TargetMol