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Cat No. | Product Name | Synonyms | Targets |
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T13099 | TC ASK 10 | ASK , MAPK | |
TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM). | |||
T22254 | Alflutinib | AST2818,ASK120067 | EGFR , P450 |
Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition. | |||
T9697 | ASK1-IN-1 | ASK | |
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays. | |||
T35897 | ASK120067 | ||
ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1]... | |||
T9377 | ASK1-IN-2 | Apoptosis , ASK , MAPK | |
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1]. | |||
T67857 | ASK1-IN-4 | ASK | |
ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM. | |||
T72064 | TASK-1-IN-1 | Potassium Channel | |
TASK-1-IN-1 is a potent and selective inhibitor of TASK-1 (Potassium Channel) (IC50: 148 nM).TASK-1-IN-1 has a reduced inhibitory effect on the TASK-3 channel with an IC50 of 1750 nM.TASK-1-IN-1 has anticancer effects. | |||
T73221 | CASK-IN-1 | ||
CASK-IN-1 is a highly potent and selective CASK inhibitor with a K d value of 0.022 μM. | |||
T61584 | ASK1-IN-3 | ||
ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarka... | |||
T22418 | S-99 | Others | |
S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research. |
Cat No. | Product Name | Synonyms | Targets |
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TN4635 | Neoechinulin A | NADPH-oxidase , Beta Amyloid , ASK , IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor | |
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) ... |
Cat No. | Product Name | Species | Expression System |
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TMPY-04563 | CASK Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Peripheral plasma membrane protein CASK, also known as calcium/calmodulin-dependent serine protein kinase, CASK and LIN2, is a nucleus, cytoplasm and cell membrane protein which belongs to theMAGUK family. CASK / LIN2... | |||
TMPY-05906 | Influenza A H1N1 (A/swine/Saskatchewan/SD0056/2014) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPH-03417 | Rotavirus A (strain Nebraska calf diarrhea virus) VP6 Protein (His) | RV-A | E. coli |
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middl... | |||
TMPH-03422 | Rotavirus A (strain Nebraska calf diarrhea virus) VP7 Protein (His & Myc) | RV-A | E. coli |
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts ... | |||
TMPY-04754 | CASK Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Peripheral plasma membrane protein CASK, also known as calcium/calmodulin-dependent serine protein kinase, CASK and LIN2, is a nucleus, cytoplasm and cell membrane protein which belongs to theMAGUK family. CASK / LIN2... | |||
TMPH-03424 | Rotavirus A (strain Nebraska calf diarrhea virus) VP4 Protein (His & Myc) | RV-A | E. coli |
Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus attachment and entr... |