5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35332 | THZ1 2HCl | THZ1 2HCl,THZ1 Dihydrochloride | CDK |
THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines. | |||
T13153 | THZ1-R | CDK | |
THZ1-R displays diminished activity for CDK7 inhibition(Kd:142 nM). | |||
T72512 | THZ1 Hydrochloride | ||
THZ1 Hydrochloride is a potent, selective covalent inhibitor of CDK7, exhibiting an IC50 value of 3.2 nM. It also targets closely related kinases CDK12 and CDK13, leading to the downregulation of MYC expression. | |||
T23458 | THZ1 Hydrochloride (1604810-83-4 free base) | THZ1 Hydrochloride | Others |
THZ1 is a covalent inhibitor of CDK7 (IC50: 3.2nM). | |||
T3664 | THZ1 | CDK7 inhibitor,THZ1 2HCl | CDK |
THZ1 (CDK7 inhibitor) is a novel selective and potent covalent CDK7 inhibitor. |