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Search Results for " ns2b-ns3 "

16

Compounds

5

Natural Products

Cat No. Product Name Synonyms Targets
T62932 NS2B/NS3-IN-2
NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 (IC50: 6.0 nM, Ki: 0.66 μM). NS2B/NS3-IN-2 significantly increases cell viability and is not cytotoxic.
T62104 NS2B/NS3-IN-5
NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively.
T60458 NS2B/NS3-IN-4
Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1].
T60881 NS2B/NS3-IN-3
NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .
T62437 NS2B/NS3-IN-6
NS2B/NS3-IN-6 (Compound 1a) is a variant of the DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 μM and 25.2 μM for the NS2B/NS3 protease of ZIKV and DENV, respectively.
T72887 NS2B/NS3-IN-7
NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells.
T78653 NS2B/NS3-IN-3 hydrochloride Virus Protease
NS2B/NS3-IN-3 hydrochloride is a Flavivirus NS2B-NS3 protease inhibitor [1].
T13397 ZINC03129319 Virus Protease
ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease.
T73097 SID-852843 Virus Protease
SID-852843 is a WNV NS2B-NS3 protease inhibitor with an IC50 value of 0.105 μM for WNV NS2B-NS3 protease.SID-852843 can be used for the study of viral infections.
T19900 ARDP0006 Others
ARDP0006 is an inhibitor of NS2B-NS3 protease.
T81642 NS2B-NS3pro-IN-1 Virus Protease
NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1].
T25171 BP13944 BP 13944,BP-13944
BP13944 is used as a potential dengue virus NS2B/NS3 protease inhibitor.
T81641 NS2B-NS3pro-IN-2 Virus Protease
Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1].
T37346 5-Hydroxytoluene-2,4-disulphonic acid diammonium
5-Hydroxytoluene-2,4-disulphonic acid diammonium, an impurity of Policresulen, is a significant NS2B/NS3 protease inhibitor, exhibiting an IC50 value of 0.48 μg/mL. It inhibits DENV2 virus replication in BHK-21 cells eff...
T37870 Bz-Nle-Lys-Arg-Arg-AMC
Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used N...
T74083 4-Hydroxy-2-methylbenzenesulfonic acid ammonium Virus Protease
4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity found in Policresulen, which serves as a powerful NS2B/NS3 protease inhibitor, exhibiting an IC50 of 0.48 μg/mL. Additionally, Policresulen is an effective s...
Cat No. Product Name Synonyms Targets
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T5429 Theaflavin 3,3'-digallate 8-Gingerol,TFDG Virus Protease , Antioxidant , HIV Protease , HSV
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...
T23664 Agathisflavone 6,8'-Biapigenin
Agathisflavone is a NS2B-NS3 proteases inhibitor of the Dengue virus serotypes 2 and 3.
T72508 Palmatine hydroxide
Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhib...
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