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Cat No. | Product Name | Synonyms | Targets |
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T62932 | NS2B/NS3-IN-2 | ||
NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 (IC50: 6.0 nM, Ki: 0.66 μM). NS2B/NS3-IN-2 significantly increases cell viability and is not cytotoxic. | |||
T62104 | NS2B/NS3-IN-5 | ||
NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM and 4.38 μM for the NS2B/NS3 protease of ZIKV and DENV2, respectively. | |||
T60458 | NS2B/NS3-IN-4 | ||
Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1]. | |||
T60881 | NS2B/NS3-IN-3 | ||
NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] . | |||
T62437 | NS2B/NS3-IN-6 | ||
NS2B/NS3-IN-6 (Compound 1a) is a variant of the DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 μM and 25.2 μM for the NS2B/NS3 protease of ZIKV and DENV, respectively. | |||
T72887 | NS2B/NS3-IN-7 | ||
NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells. | |||
T78653 | NS2B/NS3-IN-3 hydrochloride | Virus Protease | |
NS2B/NS3-IN-3 hydrochloride is a Flavivirus NS2B-NS3 protease inhibitor [1]. | |||
T13397 | ZINC03129319 | Virus Protease | |
ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease. | |||
T73097 | SID-852843 | Virus Protease | |
SID-852843 is a WNV NS2B-NS3 protease inhibitor with an IC50 value of 0.105 μM for WNV NS2B-NS3 protease.SID-852843 can be used for the study of viral infections. | |||
T19900 | ARDP0006 | Others | |
ARDP0006 is an inhibitor of NS2B-NS3 protease. | |||
T81642 | NS2B-NS3pro-IN-1 | Virus Protease | |
NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1]. | |||
T25171 | BP13944 | BP 13944,BP-13944 | |
BP13944 is used as a potential dengue virus NS2B/NS3 protease inhibitor. | |||
T81641 | NS2B-NS3pro-IN-2 | Virus Protease | |
Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1]. | |||
T37346 | 5-Hydroxytoluene-2,4-disulphonic acid diammonium | ||
5-Hydroxytoluene-2,4-disulphonic acid diammonium, an impurity of Policresulen, is a significant NS2B/NS3 protease inhibitor, exhibiting an IC50 value of 0.48 μg/mL. It inhibits DENV2 virus replication in BHK-21 cells eff... | |||
T37870 | Bz-Nle-Lys-Arg-Arg-AMC | ||
Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used N... | |||
T74083 | 4-Hydroxy-2-methylbenzenesulfonic acid ammonium | Virus Protease | |
4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity found in Policresulen, which serves as a powerful NS2B/NS3 protease inhibitor, exhibiting an IC50 of 0.48 μg/mL. Additionally, Policresulen is an effective s... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T5429 | Theaflavin 3,3'-digallate | 8-Gingerol,TFDG | Virus Protease , Antioxidant , HIV Protease , HSV |
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... | |||
T23664 | Agathisflavone | 6,8'-Biapigenin | |
Agathisflavone is a NS2B-NS3 proteases inhibitor of the Dengue virus serotypes 2 and 3. | |||
T72508 | Palmatine hydroxide | ||
Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhib... |