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Search Results for " fadd "

Targets

5

Compounds

22

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3560 Desmethylanethol trithione ADT-OH VEGFR , Akt
Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly...
T9095 Necrostatin-34 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4 RIP kinase
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
T11259 FadD32 Inhibitor-1 Others
FadD32 inhibitor -1 has anti-tuberculosis activity and is an effective FadD32 inhibitor.
T37558 Necrostatin-5 Nec-5 RIP kinase , Necroptosis
Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM.
T12203L Necrostatin 2 Others
Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-01720 DR4/TRAIL R1 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis fac...
TMPY-05388 DR5/TRAIL R2 Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-01452 DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-01437 DR5/TRAIL R2 Protein, Mouse, Recombinant (His) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-01719 DR4/TRAIL R1 Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis fac...
TMPH-02381 SlpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc) Lactobacillus acidophilus E. coli
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory...
TMPH-02588 COL12A1 Protein, Mouse, Recombinant (His) Mouse E. coli
Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold fun...
TMPY-06835 DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-05477 DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) Human HEK293
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol...
TMPJ-00246 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T...
TMPY-02213 RAIDD Protein, Human, Recombinant (His) Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu...
TMPJ-00696 NOL3 Protein, Human, Recombinant Human E. coli
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPJ-00245 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated Mouse Human Cells
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T...
TMPJ-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) Human Human Cells
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra...
TMPJ-00215 Fas/CD95 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected...
TMPJ-00430 TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra...
TMPJ-00275 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra...
TMPH-01650 PRAME Protein, Human, Recombinant (E. coli, His) Human E. coli
Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ...
TMPH-00772 Leghemoglobin C2 Protein, Glycine max, Recombinant (His) Glycine max E. coli
Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death. Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggere...
TMPH-00958 AHR Protein, Human, Recombinant (His) Human E. coli
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood...
DR5/TRAIL R2 Protein, Human, Recombinant (His)
TMPY-01185
Species: Human
Expression System: HEK293
DR4/TRAIL R1 Protein, Human, Recombinant (His)
TMPY-01720
Species: Human
Expression System: HEK293
DR5/TRAIL R2 Protein, Human, Recombinant (hFc)
TMPY-05388
Species: Human
Expression System: HEK293
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)
TMPY-01452
Species: Mouse
Expression System: HEK293
DR5/TRAIL R2 Protein, Mouse, Recombinant (His)
TMPY-01437
Species: Mouse
Expression System: HEK293
DR4/TRAIL R1 Protein, Human, Recombinant (hFc)
TMPY-01719
Species: Human
Expression System: HEK293
slpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc)
TMPH-02381
Species: Lactobacillus acidophilus
Expression System: E. coli
COL12A1 Protein, Mouse, Recombinant (His)
TMPH-02588
Species: Mouse
Expression System: E. coli
DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06835
Species: Human
Expression System: HEK293
DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated
TMPY-05477
Species: Human
Expression System: HEK293
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TMPK-00277
Species: Human
Expression System: HEK293
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
TMPJ-00246
Species: Mouse
Expression System: Human Cells
RAIDD Protein, Human, Recombinant (His)
TMPY-02213
Species: Human
Expression System: E. coli
NOL3 Protein, Human, Recombinant
TMPJ-00696
Species: Human
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
TMPJ-00245
Species: Mouse
Expression System: Human Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His)
TMPJ-00276
Species: Human
Expression System: Human Cells
Fas/CD95 Protein, Mouse, Recombinant (hFc)
TMPJ-00215
Species: Mouse
Expression System: Human Cells
TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His)
TMPJ-00430
Species: Cynomolgus
Expression System: Human Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00275
Species: Human
Expression System: Human Cells
PRAME Protein, Human, Recombinant (E. coli, His)
TMPH-01650
Species: Human
Expression System: E. coli
Leghemoglobin C2 Protein, Glycine max, Recombinant (His)
TMPH-00772
Species: Glycine max
Expression System: E. coli
AHR Protein, Human, Recombinant (His)
TMPH-00958
Species: Human
Expression System: E. coli
TargetMol