5
22
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3560 | Desmethylanethol trithione | ADT-OH | VEGFR , Akt |
Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly... | |||
T9095 | Necrostatin-34 | 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4 | RIP kinase |
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. | |||
T11259 | FadD32 Inhibitor-1 | Others | |
FadD32 inhibitor -1 has anti-tuberculosis activity and is an effective FadD32 inhibitor. | |||
T37558 | Necrostatin-5 | Nec-5 | RIP kinase , Necroptosis |
Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM. | |||
T12203L | Necrostatin 2 | Others | |
Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01185 | DR5/TRAIL R2 Protein, Human, Recombinant (His) | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPY-01720 | DR4/TRAIL R1 Protein, Human, Recombinant (His) | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis fac... | |||
TMPY-05388 | DR5/TRAIL R2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPY-01452 | DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPY-01437 | DR5/TRAIL R2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPY-01719 | DR4/TRAIL R1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 antigen, is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis fac... | |||
TMPH-02381 | SlpA Protein, Lactobacillus acidophilus, Recombinant (His & Myc) | Lactobacillus acidophilus | E. coli |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory... | |||
TMPH-02588 | COL12A1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold fun... | |||
TMPY-06835 | DR5/TRAIL R2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPY-05477 | DR5/TRAIL R2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super... | |||
TMPK-00277 | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) | Human | HEK293 |
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol... | |||
TMPJ-00246 | TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T... | |||
TMPY-02213 | RAIDD Protein, Human, Recombinant (His) | Human | E. coli |
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu... | |||
TMPJ-00696 | NOL3 Protein, Human, Recombinant | Human | E. coli |
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in... | |||
TMPJ-00245 | TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated | Mouse | Human Cells |
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T... | |||
TMPJ-00276 | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra... | |||
TMPJ-00215 | Fas/CD95 Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected... | |||
TMPJ-00430 | TRAIL R2/DR5/TNFRSF10B Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Human Cells |
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra... | |||
TMPJ-00275 | TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and tra... | |||
TMPH-01650 | PRAME Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ... | |||
TMPH-00772 | Leghemoglobin C2 Protein, Glycine max, Recombinant (His) | Glycine max | E. coli |
Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death. Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggere... | |||
TMPH-00958 | AHR Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood... |