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Search Results for " c5b "

Targets

6

Compounds

14

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9915 Eculizumab Complement System
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
T64611 Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R is a useful organic compound for research related to life sciences and the catalog number is T64611.
T74551 Avacincaptad pegol sodium
Avacincaptad pegol (ARC1905), an anti-C5 RNA aptamer, prevents the cleavage of complement factor 5 (C5) into fragments C5a and C5b. It is currently under investigation for the treatment of age-related macular degeneratio...
T31877 Freselestat ONO-PO 736,ONO-6818,ONO 6818,ONO6818
Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T74552 Non-PEGylated/naked ARC1905
ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched ...
T77190 Crovalimab
Crovalimab (SKY59; RO7112689) is a novel humanized antibody designed to target C5 in a pH-dependent manner, demonstrating binding affinities (KD) of 15.2 nM and 16.8 μM at pH levels of 7.4 and 5.8, respectively. Addition...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05057 Complement C5 Protein, Human, Recombinant (His & FLAG) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-00653 Complement C5 Protein, Human, Recombinant (Complement C5a) Human E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-06814 Complement C5 Protein, Human, Recombinant (Flag) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04133 UNC5B Protein, Human, Recombinant (His) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-00507 UNC5B Protein, Human, Recombinant (hFc) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-04003 UNC5B Protein, Rat, Recombinant (hFc) Rat HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPH-01709 Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) Human E. coli
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.
TMPJ-00585 Complement C8 gamma Protein, Human, Recombinant (His) Human E. coli
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 ...
TMPH-03270 Complement C5 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the founda...
TMPY-01292 CD55/DAF Protein, Human, Recombinant (His) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-02616 CD55/DAF Protein, Mouse, Recombinant (His) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-03004 CD55/DAF Protein, Rat, Recombinant (hFc) Rat HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-06679 CD55/DAF Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-00713 CD55/DAF Protein, Human, Recombinant (hFc) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
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