Search Result

Search Results for " ags "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T2693	AG1024	Tyrphostin AG 1024,Tyrphostin,AGS 200	Apoptosis , IGF-1R
	AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).		Apoptosis , IGF-1R
T3144	BML-284	Wnt agonist 1	Wnt/beta-catenin
	BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.		Wnt/beta-catenin
T1562	Rebamipide	Proamipide,OPC12759	Free radical scavengers , COX , Prostaglandin Receptor
	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...		Free radical scavengers , COX , Prostaglandin Receptor
T6540	Ibuprofen Lysine	Neoprofen	COX
	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.		COX
T1394	Ibuprofen	Brufen,(±)-Ibuprofe,Motrin,Advil	COX
	Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...		COX
T8820	BML-284 hydrochloride	BML-284 HCL,Wnt agonist 1 HCL	Wnt/beta-catenin
	BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.		Wnt/beta-catenin
T5858	Sertindole	Lu 23-174	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
	Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T14775	Bragsin2	6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2	Others
	Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase acti...		Others
T71081	Nagstatin
	Nagstatin is an inhibitor of N-acetyl-beta-D-glucosaminidase and is produced by Streptomyces amakusaensis MG846-fF3.
T14774	Bragsin1		Others
	Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.		Others
T79072	KRAS G12D modulator-1		Ras
	KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].		Ras

Compounds

AG1024

T2693

Synonym: Tyrphostin AG 1024,Tyrphostin,AGS 200

Target: Apoptosis, IGF-1R

BML-284

T3144

Synonym: Wnt agonist 1

Target: Wnt/beta-catenin

Rebamipide

T1562

Synonym: Proamipide,OPC12759

Target: Free radical scavengers, COX, Prostaglandin Receptor

Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil

Target: COX

BML-284 hydrochloride

T8820

Synonym: BML-284 HCL,Wnt agonist 1 HCL

Target: Wnt/beta-catenin

Sertindole

T5858

Synonym: Lu 23-174

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Autophagy

Bragsin2

T14775

Synonym: 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2

KRAS G12D modulator-1

T79072

Synonym:

Target: Ras

Cat No.	Product Name	Synonyms	Targets
TN4629	Nemoralisin C		Others
	Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines.		Others
TN4630	Nemoralisin		Others
	Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines.		Others
TN4866	Pyracrenic acid		Others
	Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. Pyracrenic acid shows DPPH radical scavenging activity. It also shows significant cytotoxic activities against human cancer cells COLO 205 a...		Others
T3930	Taraxerol acetate	Taraxeryl acetate	Phosphatase , HSV
	Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. A. roxburghiana has antidiabetic activ...		Phosphatase , HSV

Natural Products

Synonym: Taraxeryl acetate

Target: Phosphatase, HSV

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01475	Jagged 1 Protein, Human, Recombinant (His)	Human	HEK293
	Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPY-02857	GLA/alpha-Galactosidase A Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Alpha-galactosidase A, also known as Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase and GLA, is a member of the glycosyl hydrolase 27 family. GLA is used as a long-term enzyme replacement therap...
TMPY-01470	Jagged 1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPY-04930	Notch 2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev...
TMPK-00465	Notch 2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ...
TMPK-00466	Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ...
TMPY-02412	ENO1 Protein, Human, Recombinant (His)	Human	E. coli
	The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value ...
TMPY-03547	IL-10 Protein, Human, Recombinant	Human	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-01845	IL-10 Protein, Human, Recombinant (His)	Human	HEK293
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-05064	IL-10 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPK-00505	BDCA-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-01120	BDCA-2 Protein, Human, Recombinant (His)	Human	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-01121	BDCA-2 Protein, Human, Recombinant (mFc)	Human	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-01118	BDCA-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-00506	BDCA-2 Protein, Cynomolgus, Recombinant (mFc)	Cynomolgus	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-01119	BDCA-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPK-00504	BDCA-2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three...
TMPY-00073	ENO1 Protein, Rat, Recombinant (His)	Rat	E. coli
	The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value ...
TMPY-04219	IL-10 Protein, Rat, Recombinant	Rat	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-00525	IL-10 Protein, Feline, Recombinant	Feline	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-00466	IL-10 Protein, Sus scrofa (Pig), Recombinant	Sus scrofa (Pig)	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...