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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22409 | Proguanil | chloroguanide,chlorguanide | Others |
Proguanil, a prophylactic antimalarial drug, inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of pyrimidines and purines, which are essential for DNA synthesis and cell multiplication... | |||
T4382 | Proguanil hydrochloride | Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil | Others , Dehydrogenase , DNA/RNA Synthesis , Antifolate , Parasite |
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ... | |||
T12545 | Proguanil D6 | Others | |
Proguanil D6 is the deuterium labeled Proguanil, and is an agent of prophylactic antimalarial. | |||
T5420 | Cycloguanil hydrochloride | Chloroguanide Triazine | Parasite , Drug Metabolite |
Cycloguanil hydrochloride (Chloroguanide Triazine) is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, r... | |||
T69591 | Cycloguanil nitrate | ||
Cycloguanil nitrate is a dihydrofolate reductase inhibitor and is a metabolite of the antimalarial drug proguanil. |