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Cat No. | Product Name | Synonyms | Targets |
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T11205 | Ent-Ezetimibe | ent-SCH 58235 | Others |
Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhib... | |||
T1593 | Ezetimibe | SCH 58235 | Others , Nrf2 , NPC1L1 , Autophagy |
Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption. | |||
T11251 | Ezetimibe ketone | EZM-K | Nrf2 , NPC1L1 |
Ezetimibe, a compound known as a Niemann-Pick C1-like1 (NPC1L1) inhibitor and a potent Nrf2 activator, effectively inhibits cholesterol absorption. Additionally, Ezetimibe ketone (EZM-K) represents a phase-I metabolite o... | |||
T70848 | AZD-4121 tert-butylammonium | ||
AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia. | |||
T70849 | AZD-4121 | ||
AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia. | |||
T11003 | Desfluoro-ezetimibe | Others | |
Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective N... | |||
T11250 | Ezetimibe-d4 | SCH 58235 D4 | Others |
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2. | |||
T16322 | Nicodicosapent | Others | |
Nicodicosapent is a fatty acid niacin conjugate. It is also an inhibitor of the sterol regulatory element-binding protein (SREBP). The sterol regulatory element-binding protein (SREBP) is a key regulator of cholesterol m... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03755 | Ppard Protein, Human, Recombinant (His) | Human | E. coli |
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosape... |