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Search Result

Search Results for " nae "

Targets

Apoptosis E1/E2/E3 Enzyme

24

Compounds

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8816 NAE-IN-M22 NEDD8 inhibitor M22 Apoptosis , E1/E2/E3 Enzyme
NAE-IN-M22 (NEDD8 inhibitor M22) is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can i...
T6332 Pevonedistat MLN4924 E1/E2/E3 Enzyme , NEDD8
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM). Pevonedistat can be used for the treatment of myelodysplastic syndromes (MDS) and also has antitumor activity.
T13090 TAS4464 hydrochloride E1/E2/E3 Enzyme , NEDD8
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
T5374 NAcM-OPT E1/E2/E3 Enzyme , NEDD8
NAcM-OPT is a specific, reversible inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 （IC50: 79 nM).
T16335 Nonaethylene glycol monododecyl ether Nonaoxyethylene monododecyl ether,Polidocanol Others
Nonaethylene glycol monododecyl ether (Polidocanol) is a nonionic surfactant and polyethylene glycol (PEG) detergent. It can be used to form initial coalesced O/W emulsion droplets and for protein separation and purifica...
T76249 RNAENFDRF
RNAENFDRF (βIIPKC624-632) conjugated to TAT47-57, a cell-permeable peptide, forms SAMβA, a rationally designed peptide that selectively antagonizes Mfn1-βIIPKC association. SAMβA acts as a selective inhibitor of mitofusi...
T16337 Nonaethylene glycol Others
Nonaethylene glycol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T16336 Nonaethylene glycol monomethyl ether Others
Nonaethylene glycol monomethyl ether, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
T25847 NAEPA
NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.
T76249L RNAENFDRF TFA
RNAENFDRF (βIIPKC624-632) TFA is conjugated to the cell permeable peptide TAT47-57, which can be used to form an inhibitory peptide SAMβA. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAM...
T33578 Naepaine hydrochloride
Naepaine hydrochloride is a biochemical.
T124493 Senaetnine
Senaetnine is a useful organic compound for research related to life sciences and the catalog number is T124493.
T126132 Tabernaecorymbosine A
Tabernaecorymbosine A is a useful organic compound for research related to life sciences and the catalog number is T126132.
T13412 ZM223 ZM-223 E1/E2/E3 Enzyme
ZM223 is an inhibitor of NEDD8 activating enzyme (NAE).
T16102 ML-792 E1/E2/E3 Enzyme
ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and >100 μM, respectively), ML-792 is an effective and selective inhi...
T63800 ZM223 hydrochloride
ZM223 hydrochloride is a potent, non-covalent, orally active inhibitor of NEDD8 activase (NAE).
T68059 Ebalzotan
NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.
T69577 LEI-301
LEI-301 is a novel potent inhibitor for the PLAAT family members, reducing the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5.
T28007 MDPD
MDPD is an enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis. MDPD alleviates the growth inhibitory effects of NAE 12:0, in part by enhancing the enzymatic activity of Arabid...
T13412L ZM223 hydrochloride (2031177-48-5 free base) ZM223 hydrochloride Serine Protease
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
T37530 Glycerophospho-N-Arachidonoyl Ethanolamine
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1...
T38049 Glycerophospho-N-Palmitoyl Ethanolamine
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating t...
T16117 Pevonedistat hydrochloride MLN4924 hydrochloride Others
Pevonedistat hydrochloride is an effective and selective inhibitor of NEDD8-activating enzyme (IC50: 4.7 nM).
T13090L TAS4464 E1/E2/E3 Enzyme
TAS4464 is a highly potent and selective inhibitor of the NEDD8 activating enzyme (IC50: 0.955 nM).

Recombinant Proteins

Species：
Dermatophagoides farinae (2)
Penaeus monodon (2)
Acetoanaerobium sticklandii (1)
Human (1)
Metapenaeus ensis (1)
Penaeus sp. (1)
Expression System：
E. coli (6)
Baculovirus-Insect Cells (1)
HEK293 (1)
Tag：
His (3)
N-terminal 6xHis-SUMO-tagged (2)
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged (1)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPH-03088 Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) Penaeus monodon E. coli
Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-06675 Met e 1 Protein, Metapenaeus ensis, Recombinant Metapenaeus ensis E. coli
Met e 1 Protein, Metapenaeus ensis, Recombinant is expressed in E. coli. The predicted molecular weight is 32.7 kDa.
TMPY-05140 Der f 1 Protein, Dermatophagoides farinae, Recombinant (His) Dermatophagoides farinae HEK293
Der f 1 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 35.9 kDa. Accession number: Q58A71
TMPH-03090 SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO) Penaeus sp. E. coli
Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.
TMPY-05078 Der f 2 Protein, Dermatophagoides farinae, Recombinant (His) Dermatophagoides farinae E. coli
Der f 2 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 15 kDa. Accession number: Q00855.1
TMPH-00016 Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc) Acetoanaerobium sticklandii E. coli
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
TMPH-03089 SCP Protein, Penaeus monodon, Recombinant (His & SUMO) Penaeus monodon E. coli
SCP Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
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