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Cat No. | Product Name | Synonyms | Targets |
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T4570 | Pipobroman | Vercyte,A-8103,Amedel | Others , DNA Alkylator/Crosslinker |
Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, wit... | |||
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
TQ0059 | Ilorasertib | ABT-348 | VEGFR , FLT , c-RET , PDGFR , Aurora Kinase |
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ... | |||
T22776 | Ezatiostat hydrochloride | TLK199 HCl,TER199 | Glutathione Peroxidase |
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr... | |||
T76975 | Tomaralimab | OPN-305 | TLR |
Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS). | |||
T6332 | Pevonedistat | MLN4924 | E1/E2/E3 Enzyme , NEDD8 |
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM). Pevonedistat can be used for the treatment of myelodysplastic syndromes (MDS) and also has antitumor activity. | |||
T64133L | Laniquidar TFA | Laniquidar TFA(197509-46-9 Free base),R101933 | P-gp |
Laniquidar TFA (R101933) is a novel orally available non-competitive P-glycoprotein (P-gp) inhibitor with an IC50 value of 0.51 μM.Laniquidar has limited bioavailability and can be used to modulate the multidrug resistan... | |||
T16384 | Olutasidenib | FT-2102 | Dehydrogenase , Isocitrate Dehydrogenase (IDH) |
Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Olutasidenib is a highly effective, brain penetrant, and selective inhibitor of the mutant Iso... | |||
T76911 | Asunercept | ||
Asunercept (APG101; CAN008), a soluble CD95-Fc fusion protein, selectively targets and binds to CD95L, effectively disrupting CD95/CD95L signaling. It is utilized in research for treating glioblastoma multiforme (GBM), m... | |||
T64133 | Laniquidar | ||
Laniquidar (R101933) is a third generation non-competitive inhibitor of P-glycoprotein (P-gp) (IC50: 0.51 μM) with limited oral bioavailability. It can also be used to modulate multidrug resistance transporters. |
Cat No. | Product Name | Species | Expression System |
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TMPY-01267 | 14-3-3 epsilon Protein, Human, Recombinant (GST) | Human | E. coli |
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co... | |||
TMPY-01274 | 14-3-3 epsilon Protein, Human, Recombinant | Human | E. coli |
YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co... | |||
TMPY-03507 | PPC-DC Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of... | |||
TMPY-03227 | CISD1 Protein, Human, Recombinant (His) | Human | E. coli |
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe... | |||
TMPY-01410 | IL-3R alpha/CD123 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-05418 | IL-3R alpha/CD123 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-06744 | IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-00592 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-04034 | IL-3R alpha/CD123 Protein, Canine, Recombinant (His) | Canine | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-06793 | IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-00076 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-06715 | IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-02043 | PARK7/DJ-1 Protein, Human, Recombinant (His) | Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress.... |
Cat No. | Product Name | ||
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L8400 | Hematonosis Compound Library | 524 compounds | |
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS); |