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Search Results for " dcaf16 "

5

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T75139 TMX1
TMX1 is a molecular glue degrader that covalently targets BRD4. It selectively recruits DCAF16 to the BRD4 BD2 domain, leading to the degradation of BRD4 [1].
T81780 MMH2
MMH2 is a novel molecular glue degrader targeting BRD4 by facilitating the recruitment of CUL4 and DCAF16 ligases to BRD4's second bromodomain (BRD4 BD2) [1].
T81781 MMH1
MMH1, a novel molecular glue degrader of BRD4, operates by enlisting the CUL4 and DCAF16 ligases to target the second bromodomain (BRD4 BD2) [1].
T18060 KB02-JQ1 Others
KB02-JQ1 is a potent and specific proteolysis targeting chimera (PROTAC) that specifically degrades BRD4, acting as a molecular glue. It does not degrade BRD2 or BRD3. The mechanism of action involves covalent modificati...
T18061 KB02-SLF Others
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of p...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01203 DCAF16 Protein, Human, Recombinant (His & Myc) Human E. coli
Functions as a substrate recognition component for CUL4-DDB1 E3 ubiquitin-protein ligase complex, which mediates ubiquitination and proteasome-dependent degradation of nuclear proteins. DCAF16 Protein, Human, Recombinant...
TargetMol