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Search Results for " c99 "

Targets

10

Compounds

Cat No. Product Name Synonyms Targets
T6058 LY2886721 Beta-Secretase , BACE
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.
T8719 SC99 Apoptosis , JAK , STAT
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...
T23602 ABC99 ABC 99,ABC-99 Wnt/beta-catenin
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.
T12071 MKC9989 IRE1
MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.
T29064 UNC9975 UNC-9975
UNC9975 is an analog of aripiprazole and a β-arrestin-biased D2R agonist.
T29065 UNC9994 UNC-9994,UNC 9994
UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.
T29066 UNC9995 UNC-9995,UNC 9995
UNC9995 is a β-Arrestin-Biased Dopamine D2 Receptor agonist (β-Arrestin, EC50 = 120 nM; Emax = 88%).
T62853 UNC9994 hydrochloride
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates β- arresttin recruitment and signal transduction. UNC9994 hydrochloride is a ...
T116837 TLC9995-0188
Tyrosine-protein kinase ABL, IC50: 1500 nM
T6870 L-685458 L-685,458 Apoptosis , Gamma-secretase
L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
TargetMol