23
11
2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27527 | HBF-0259 | HBF 0259 | Antiviral |
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV... | |||
T12719 | RG7834 | RO 7020322 | HBV |
RG7834 (RO 7020322) is a highly selective and orally bioavailable inhibitor of HBV(HBsAg and HBeAg and HBV DNA with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells). | |||
T79469 | HBV-IN-34 | HBV | |
HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA and 0.044 μM for HBsAg [1]. | |||
T62256 | HBV-IN-11 | ||
HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM). | |||
T62144 | HBV-IN-13 | ||
HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg). | |||
T76969 | Tuvirumab | ||
Tuvirumab (OST 577; SDZ-OST 577), a human IgG1 subclass monoclonal antibody, targets HBV surface antigen (HBsAg) by binding to it with high specificity and affinity (K=3.6 nM). This compound holds promise for research in... | |||
T77063 | Libivirumab | ||
Libivirumab (17.1.41), a humanized monoclonal antibody targeting hepatitis B virus (HBV), demonstrates neutralizing activity with half maximal inhibitory concentrations (IC50) of 35 ng/mL for HBsAg and 130 ng/mL for HBeA... | |||
T23407 | Surface antigen (208-215) [Hepatitis B Virus] | Others | |
The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat... | |||
T62579 | HBV-IN-19 | ||
HBV-IN19 has inhibitory effects on hepatitis B virus (HBV) infection. HBV-IN19 inhibits HBsAg secretion and/or production and can be used in the study of HBV infection (e.g. chronic HBV infection). | |||
T76530 | HBV Seq2 aa:208-216 | ||
HBV Seq2 aa:208-216, a CD8 epitope peptide derived from HBsAg, is investigated within the context of the Large envelope protein from the Hepatitis B virus [1]. | |||
T62626 | HBV-IN-12 | ||
HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.001 μM < EC50 ≤ 0.05 μM). HBV-IN-12 is anti-HBV DNA (0.001 μM < EC50 ≤ 0.02 μM). | |||
T76528 | Hepatitis b virus pre-s region (120-145) | ||
Hepatitis B Virus Pre-S Region (120-145) is a preS2 peptide that effectively blocks the attachment of single-chain Fv fragment (scFv) or IgG to recombinant Hepatitis B surface antigen (r-HBsAg) [1]. | |||
T76529 | HBV Seq2 aa:28-39 | ||
HBV Seq2 aa:28-39, a Hepatitis B surface antigen (HBsAg) peptide, specifically binds to Major Histocompatibility Complex (MHC) class I molecules, as evidenced in sources [1] [2]. | |||
T62433 | (5S,8R)-HBV-IN-10 | ||
(5S,8R)-HBV-IN-10 is an isomer of compound 6 (WO2021204258A1). Compound 6 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.1 μM< EC50≤1 μM). | |||
T62434 | HBV-IN-10 | ||
HBV-IN-10 is an isomer of compound 6 (WO2021204258A1). Compound 6 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.1 μM < EC50 ≤ 1 μM). | |||
T73283 | HBV-IN-32 | ||
HBV-IN-32, a potent inhibitor of covalently closed circular DNA (cccDNA), exhibits significant anti-Hepatitis B Virus (HBV) activity by achieving an IC50 of 0.14 µM against HBsAg. Additionally, it impedes cell growth. | |||
T73282 | HBV-IN-31 | ||
HBV-IN-31, a potent inhibitor of covalently closed circular DNA (cccDNA), demonstrates significant anti-HBV activity by inhibiting cell growth and exhibiting an IC50 value of 0.13 µM for HBsAg. | |||
T69709 | GST-HG131 | ||
GST-HG131, a dihydrobenzopyridooxazepine (DBP) series compound, specifically inhibits hepatitis B virus (HBV) surface antigen. It demonstrates excellent HBV antigens inhibition, with EC50 values of 28.2 nM (HBsAg) and 16... | |||
T62247 | HBV-IN-9 | ||
HBV-IN-9 (example 20) is a potent inhibitor of HBsAg (HBV surface antigen) with an IC50 value of 10 nM. HBV-IN-9 (example 20) is also an inhibitor of HBV DNA replication with an IC50 value of 0.15 nM. | |||
T63937 | HBV-IN-19 TFA | ||
HBV-IN19 TFA inhibits the secretion and/or production of HBsAg and has an inhibitory effect on hepatitis B virus (HBV) infection and can be used in studies of HBV infection, including chronic HBV infection. | |||
T67868 | Oleana-2,12-dien-28-oic acid | HBV | |
Oleana-2,12-dien-28-oic acid is an HBsAg and HBeAg inhibitor that obviously inhibit HBV deoxyribonucleic acid (HBV-DNA) replication in HepG2.2.15 cells. Oleana-2,12-dien-28-oic acid for the study of hepatitis B virus inf... | |||
T62115 | HBV-IN-24 | ||
HBV-IN-24 (compound (2 S, 6S)-1a) is a potent inhibitor of HBV. HBV-IN-24 is a strong inhibitor of HBV DNA (EC50: 0.6 nM), HBsAg (EC50: 0.6 nM) and HBeAg (EC50: 4.6 nM). antiviral effect and was able to improve neurotoxi... | |||
T35771 | Destruxin B2 | ||
Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg)... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1482 | Chamaechromone | P450 , HBV | |
Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity. | |||
T3794 | Pentagalloylglucose | Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose | Influenza Virus |
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten... | |||
T33679 | Nirtetralin | (+-)-Nirtetralin | |
Nirtetralin suppresses HBsAg and HBeAg expression. | |||
TN6420 | Sikokianin A | ||
Sikokianin A shows in vitro antiviral activity against HBsAg secretion. | |||
TN2220 | Sophoranol | (+)-Sophoranol | HBV |
(+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secretion and against HBeAg secretion. | |||
TN4750 | Periglaucine A | HBV | |
Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells. | |||
TN4751 | Periglaucine B | HBV | |
Periglaucine B can inhibit hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells. | |||
T79976 | Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside | HBV | |
Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside serves as an anti-hepatitis B virus (anti-HBV) agent, effectively inhibiting the secretion of HBV surface antigen (HBsAg) and HBV e antigen (HBeAg) in the Hep G2.2... | |||
TN2417 | Furomollugin | Antifection | |
Furomollugin has antiviral activity, it can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 = 2.0 micrograms/mL, in human hepatoma Hep3B cells. | |||
T79975 | Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside | HBV | |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside (Compound 1), a lignan with anti-HBV activity, exhibits selectivity by targeting the HBV surface antigen (HBsAg) with an IC50 of 0.58 mM, whereas its activity ag... | |||
T81531 | Pedunculosumoside F | ||
Pedunculosumoside F, a homoflavonoid glucoside extracted from Ophioglossum pedunculosum, exhibits cytotoxicity against HepG2 22.15 cells, presenting a CC50 value of 56.7 μM, yet lacks anti-HBV activity. Conversely, its a... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00810 | Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) | HDV | Yeast |
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging ... | |||
TMPH-00816 | HBV-A subtype adw2 (strain Rutter 1979) Large envelope protein (His) | HBV-A | in vitro E. coli expression system |
The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell rec... |