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Search Results for " cyclophosphamide "

Targets

17

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T0707L Cyclophosphamide DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T0707 Cyclophosphamide hydrate Cyclophosphamide monohydrate DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
T35643 4-hydroperoxy Cyclophosphamide 4-hydroperoxy Cyclophosphamide,4-OOH-CY
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide. 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitoch...
T35645 4-oxo Cyclophosphamide
4-oxo Cyclophosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1,2It is formed from cyclophosphamide through a 4-hydroxycyclophosphamide intermediate by aldehyde dehydrogenases.2 1.Struck, R.F...
T1414 Sodium 2-mercaptoethanesulfonate Mitexan,Uromitexan,Mesna,Mesnum,Mesnex Others
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
T38410 Phosphoramide mustard DNA Alkylation , Drug Metabolite
Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.
T1055 Ifosfamide NSC109724,Isophosphamide DNA Alkylator/Crosslinker , DNA/RNA Synthesis
Ifosfamide (NSC-109724) alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic acti...
T37108 Carboxyphosphamide
Carboxyphosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1It is formed from cyclophosphamideviaoxidation of the intermediate metabolite aldophosphamide by aldehyde dehydrogenase. 1.Manthey, ...
T68592 Mafosfamide sodium
Mafosfamide sodium is an oxazaphosphorine derivative with antineoplastic properties. It alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis.
T29845 Alcophosphamide NSC 153182,Hydroxyphosphamide
Alcophosphamide is a urinary metabolite of cyclophosphamide which may be used in proteomics research.
T24102 GR-203040 HCl GR 203040,GR-203040 hydrochloride,GR-203040,GR203040
GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR-203040 is a selective NK1 receptor antagonist.
T68434 Mafosfamide
Mafosfamide is a synthetic oxazaphosphorine derivative with antineoplastic properties. It alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis.
T25723 L-Ifosfamide (+)-Ifosfamide
L-Ifosfamide is nitrogen mustard, a chemotherapeutic antineoplastic, and more precisely an alkylating agent structural analog of cyclophosphamide with respect to which presents some differences regard to the antitumor ac...
T36701 Phosphoramide mustard (cyclohexanamine)
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA d...
T70304 CI-898 HCl
CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1...
T63464 ERCC1-XPF-IN-1
ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM). ERCC1-XPF-IN-1 inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic e...
T71549 RKS-262
RKS262 is a specific cyclin/CDK inhibitor. RKS262 was identified by structural optimization of Nifurtimox which is currently undergoing phase II clinical trials to treat high-risk neuroblastoma. In a NCI(60) cell-line as...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02299 ALDH3A1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...
TargetMol