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Search Result

Search Results for " chf "

Targets

Estrogen Receptor/ERR

27

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T68042 CHF-4227 Chf4227,Chf 4227 Estrogen Receptor/ERR
CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations.
T30875 CHF 1255 CHF1255,CHF-1255
CHF 1255 is a potential drug for the treatment of heart failure.
T33711L Nolomirole HCl CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride Dopamine Receptor , Norepinephrine
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure.
T38625 Tanimilast CHF-6001 PDE
Tanimilast (CHF-6001) is a novel, potent and selective phosphodiesterase 4 inhibitor with an IC 50 value of 0.026 ± 0.006 nM.Tanimilast has potent anti-inflammatory activity and is indicated for topical use in the lungs....
T30878 CHF-2993 CHF 2993,5NY5Q1OUZ3,UNII-5NY5Q1OUZ3,CHF2993
CHF-2993 is a bio-active chemical.
T30876 CHF 2819 Ganstigmine HCl,CHF-2819,Ganstigmine hydrochloride,CHF2819
CHF 2819 is a novel orally active acetylcholinesterase inhibitor (AChE) developed for the treatment of Alzheimer's disease (AD). CHF 2819 is a selective inhibitor of AChE, it is 115 times more potent against this enzyme ...
T70572 CHF-2060
CHF-2060 is a novel acetylcholinesterase inhibitor.
T30879 CHF-5022 UNII-JO8EVV007Q,CHEMBL196246,CHF5022
CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).
T30877 CHF-1024 UNII-HPH2L3QA2F
CH-5137291 is a pure AR antagonist with AR nuclear translocation inhibition activity. It inhibits castration and prevents the growth of prostate cancer cells.
T27606 Indantadol HCl CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol MAO , NMDAR
Indantadol HCl (CHF-3381) is a NMDA antagonist and nonselective MAO inhibitor.
T13992 CHF5407 SVT-47060 AChR
CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on bronchospasm and may be used in the study of respiratory disorders.CHF...
T70376 CHF-6366
CHF-6366 is a dual-action chemical compound acting as a potent M3 muscarinic antagonist and β2-adrenergic receptors agonist, with respective pK i values of 10.4 and 11.4. Additionally, it exhibits weak calcium channel in...
T33711 Nolomirole CHF1025,CHF-1025,CHF 1025
Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.
T2262 Itanapraced CHF5074,CSP-1103 Beta Amyloid , Gamma-secretase
Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).
T70375 ZEN-2759 Epigenetic Reader Domain
ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).
T69233 Ganstigmine
Ganstigmine is an acetylcholinesterase inhibitor for Alzheimer's disease.
T70638 P38-α MAPK-IN-5
P38-α MAPK-IN-5 is a potent inhibitor of p38α, demonstrating inhibitory concentrations (IC50) of 0.1 nM for p38α, 0.2 nM for p38β, 944 nM for p38γ, and 4100 nM for p38δ. It exhibits anti-inflammatory properties and holds...
T1461 Candesartan CV 11974 RAAS
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T71944 FGF/PDGF/VEGF RTK Inhibitor
FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...
T71937 Nitrodenafil
Nitrodenafil is a related compound of Sildenafil -- a phosphodiesterase inhibitor.
T18720 FCHFHS-ST7612AA1 Others
FCHFHS-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].
T30501 BMS-193884 BMS193884,BMS 193884
BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.
T36008 Nebentan potassium
Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned ...
T13195 Trandolapril D5 RU44570 D5 Others
Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).
T71065 Quinapril-d5
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapr...
T36007 Nebentan
Nebentan (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan inhibits [125I] endothelin-1 binding to cloned human endothelin ETA...

Compounds

CHF-4227
T68042
Synonym: Chf4227,Chf 4227
Target: Estrogen Receptor/ERR
CHF 1255
T30875
Synonym: CHF1255,CHF-1255
Target:
Nolomirole HCl
T33711L
Synonym: CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride
Target: Dopamine Receptor, Norepinephrine
Tanimilast
T38625
Synonym: CHF-6001
Target: PDE
CHF-2993
T30878
Synonym: CHF 2993,5NY5Q1OUZ3,UNII-5NY5Q1OUZ3,CHF2993
Target:
CHF 2819
T30876
Synonym: Ganstigmine HCl,CHF-2819,Ganstigmine hydrochloride,CHF2819
Target:
CHF-2060
T70572
Synonym:
Target:
CHF-5022
T30879
Synonym: UNII-JO8EVV007Q,CHEMBL196246,CHF5022
Target:
CHF-1024
T30877
Synonym: UNII-HPH2L3QA2F
Target:
Indantadol HCl
T27606
Synonym: CHF-3381,CMP-3381,GT-3381,V-3381,CNP-3381,Indantadol
Target: MAO, NMDAR
CHF5407
T13992
Synonym: SVT-47060
Target: AChR
CHF-6366
T70376
Synonym:
Target:
Nolomirole
T33711
Synonym: CHF1025,CHF-1025,CHF 1025
Target:
Itanapraced
T2262
Synonym: CHF5074,CSP-1103
Target: Beta Amyloid, Gamma-secretase
ZEN-2759
T70375
Synonym:
Target: Epigenetic Reader Domain
Ganstigmine
T69233
Synonym:
Target:
p38-α MAPK-IN-5
T70638
Synonym:
Target:
Candesartan
T1461
Synonym: CV 11974
Target: RAAS
Trandolapril
T5329
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
FGF/PDGF/VEGF RTK Inhibitor
T71944
Synonym:
Target:
Nitrodenafil
T71937
Synonym:
Target:
FCHFHS-ST7612AA1
T18720
Synonym:
Target: Others
BMS-193884
T30501
Synonym: BMS193884,BMS 193884
Target:
Nebentan potassium
T36008
Synonym:
Target:
Trandolapril D5
T13195
Synonym: RU44570 D5
Target: Others
Quinapril-d5
T71065
Synonym:
Target:
Nebentan
T36007
Synonym:
Target:

Recombinant Proteins

Species：
CCHFV (2)
Mouse (1)
Expression System：
E. coli (3)
Tag：
N-6His (1)
N-terminal 6xHis-B2M-tagged (1)
N-terminal MBP-tagged and C-terminal 6xHis-tagged (1)
Cat No. Product Name Species Expression System
TMPH-00447 CCHF virus (isolate C68031) Nucleoprotein/NP Protein (B2M & His) CCHFV E. coli
CCHF virus (isolate C68031) Nucleoprotein/NP Protein (B2M & His) is expressed in E. coli.
TMPH-00446 CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP) CCHFV E. coli
CCHF virus (strain Nigeria/IbAr10200/1970) Envelopment polyprotein (His & MBP) is expressed in E. coli.
TMPJ-01443 HChFc2 Protein, Mouse, Recombinant (His) Mouse E. coli
Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase I...
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