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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13006 | ST-193 | Virus Protease | |
ST-193 is a potent inhibitor of broad-spectrum arenavirus(Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively). | |||
T11138L | LHF-535 | Virus Protease , Antiviral | |
LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively. | |||
T12711 | Retro-2 cycl | RN 1-001 | Virus Protease |
Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 160 μM, respectively),with antiviral agent. | |||
T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T71996 | VU0621623 | ||
VU0621623 is an arenavirus multiplication inhibitor which blocks lymphocytic choriomeningitis virus (LCMV) cell entry. | |||
T62045 | ST-193 hydrochloride | ||
ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor. ST-193 hydrochloride inhibits Guanarito, Junin, Lassa and Machupo virus with IC50s of 0.44, 0.62, 1.4 and 3.1 nM, respectively. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1805 | 5,7-Dihydroxychromone | 5,7-Dihydroxy-4H-Chromen-4-One | Others , Virus Protease , PARP , Caspase , Nrf2 |
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai... | |||
T69225 | Verrucarin J | Muconomycin B | |
Verrucarin J (Muconomycin B) is a metabolite of the Myrothecium fungus family. Verrucarin J generates reactive oxygen species ( ROS ) and induces apoptosis of cancer cell lines, such as A549, HCT 116 and SW-620 cells. Ve... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02366 | Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) | JUNV | E. coli |
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ... |