VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.

Cat. No.	Product name	CAS No.	Purity
T9928	Ranibizumab	347396-82-1	98%
T9928	Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121, and...
TN4343	Jaceidin	10173-01-0	98%
TN4343	Jaceidin (Quercetagetin 3,3',6-trimethyl ether) is a membrane-permeable inhibitor of VEGFR with anti-tumor activities.
T6193	Dovitinib Dilactic Acid	852433-84-2	98%
T6193	Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3...
T12145	N-Desethyl Sunitinib	356068-97-8	98%
T12145	N-Desethyl Sunitinib (SU-11662) is a sunitinib metabolite.
T14055	5Z-7-Oxozeaenol	253863-19-3	98%
T14055	5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK...
T5001	Nintedanib esylate	656247-18-6	99.96%
T5001	Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β
T12598	Pz-1	1800505-64-9	99.95%
T12598	Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.
T2496	(Z)-Semaxinib	194413-58-6	99.94%
T2496	(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR...
T6091	CP-673451	343787-29-1	99.93%
T6091	CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiog...
T2586	Cabozantinib	849217-68-1	99.88%
T2586	Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Caboz...
T16909	Sorafenib-d3	1130115-44-4	99.88%
T16909	Sorafenib-d3 (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, re...
T1792	Regorafenib	755037-03-7	99.87%
T1792	Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active...
T2638	Gandotinib	1229236-86-5	99.86%
T2638	LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JA...
T2056L	UNC0064-12 hydrochloride (1430089-64-7(free base))	T2056L	99.85%
T2056L	UNC0064-12 hydrochloride is an inhibitor of VEGFR2.
T1777	Nintedanib	656247-17-5	99.85%
T1777	Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108...
T7493	AG-13958	319460-94-1	99.84%
T7493	AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.
T0097L	Pazopanib	444731-52-6	99.84%
T0097L	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibi...
T5349	SCR-1481B1	1174161-86-4	99.83%
T5349	SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor
T0520	Lenvatinib	417716-92-8	99.8000%
T0520	Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib h...
T79860	TIE-2/VEGFR-2 kinase-IN-5	1014407-83-0	99.79%
T79860	TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical resea...