T31011 |
Coralyne chloride
|
38989-38-7
|
99.35%
|
|
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifie...
|
T1294 |
Fleroxacin
|
79660-72-3
|
99.34%
|
|
Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
|
T3481 |
Bimolane
|
74550-97-3
|
99.29%
|
|
Bimolane is a topoisomerase II inhibitor.
|
T0974 |
Novobiocin Sodium
|
1476-53-5
|
99.28%
|
|
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derive...
|
T0909 |
Nalidixic acid
|
389-08-2
|
99.22%
|
|
Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of ba...
|
TN1375 |
α-Lapachone
|
4707-33-9
|
99.17%
|
|
α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.
|
T8498 |
EIDD-1931
|
3258-02-4
|
99.14%
|
|
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus...
|
T1020 |
Doxorubicin hydrochloride
|
25316-40-9
|
99.13%
|
|
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). ...
|
T13231L |
Trovafloxacin mesylate
|
147059-75-4
|
99.12%
|
|
Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the activity of DNA gyrase and topoisomerase IV, enzymes involved in DNA replication. ...
|
T1121 |
Podofilox
|
518-28-5
|
99.07%
|
|
Podofilox ((+)-Shikonin) is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken int...
|
T5S1952 |
9-Methoxycamptothecin
|
39026-92-1
|
99.03%
|
|
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
|
TN1037 |
Groenlandicine
|
38691-95-1
|
99.03%
|
|
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recom...
|
T0425L |
Pefloxacin Mesylate Dihydrate
|
149676-40-4
|
99.03%
|
|
Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase).
|
T28475 |
Pyrazoloacridine
|
99009-20-8
|
98.99%
|
|
Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine ...
|
T16286 |
Nelonemdaz
|
640290-67-1
|
98.95%
|
|
Neu2000 is an uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor.
|
T5S0761 |
Nitidine chloride
|
13063-04-2
|
98.91%
|
|
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721...
|
T26339L |
XR-11576 HCl
|
T26339L
|
98.89%
|
|
XR-11576 HCl is a novel orally active dual topoisomerase I and II inhibitor with antitumor activity.
|
T4614 |
Ellipticine hydrochloride
|
5081-48-1
|
98.85%
|
|
Ellipticine hydrochloride (NSC-71795 (hydrochloride)) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.
|
T1174 |
Topotecan hydrochloride
|
119413-54-6
|
98.76%
|
|
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
|
T6628 |
Pirarubicin
|
72496-41-4
|
98.66%
|
|
Pirarubicin (Theprubicin) is an anthracycline antibiotic. It is also a DNA/RNA synthesis inhibitor that intercalates into DNA and interacts with topoisomerase II...
|