TN1775 |
Isocryptotanshinone
|
22550-15-8
|
98%
|
|
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative r...
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
T74950 |
Antitumor agent-73
|
2812356-72-0
|
98%
|
|
Antitumor Agent-73, a derivative of Diosgenin, both impedes STAT3 signaling and exogenously stimulates Pdia3/ERp57. This compound demonstrates significant antine...
|
T11449 |
Golotimod hydrochloride (229305-39-9 free base)
|
T11449
|
98%
|
|
Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis...
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
T15234 |
ENMD-1198
|
864668-87-1
|
98%
|
|
ENMD-119 is a 2-methoxyestradiol analog with antiproliferative and antiangiogenic activity. It is suitable for inhibiting HIF-1α and STAT3 in human HCC cells.
|
TN4356 |
Jolkinolide A
|
37905-07-0
|
98%
|
|
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly in...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4604 |
Myricanone
|
32492-74-3
|
98%
|
|
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
|
TN4490 |
Manassantin B
|
88497-88-5
|
98%
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV ...
|
TN1985 |
Neoprzewaquinone A
|
630057-39-5
|
98%
|
|
Neoprzewaquinone A (NEO), an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 ...
|
T11449L |
Golotimod
|
229305-39-9
|
98%
|
|
Golotimod is an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and spl...
|
TP2222L |
APTSTAT3-9R acetate
|
|
98%
|
|
APTSTAT3-9R acetate is a selective peptide binding STAT3 with antiproliferative and antitumor activity. APTSTAT3-9R acetate and inhibits STAT3 activation and dow...
|
T4571 |
Balsalazide
|
80573-04-2
|
98%
|
|
Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
|
T71550 |
STAT3-IN-8
|
1041438-68-9
|
98%
|
|
"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."
|
T24838 |
Stafib-1
|
1688703-26-5
|
98%
|
|
Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.
|
TN1013 |
Cucurbitacin D
|
3877-86-9
|
98%
|
|
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.
|
T14330 |
Ascochlorin
|
26166-39-2
|
98%
|
|
Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, mediates its anti-tumor effects predominantly through the suppression of STAT3 signaling cascade. Ascochlor...
|
T121011 |
TLC1566-0618
|
708218-62-6
|
98%
|
|
TLC1566-0618 shows antitumor activity and targets stat.
|
TN3541 |
Broussonin E
|
90902-21-9
|
98%
|
|
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathwa...
|