ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.

Cat. No.	Product name	CAS No.	Purity
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline	500272-00-4	99.49%
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal s...
T6917	Oleuropein	32619-42-4	99.46%
T6917	Oleuropein is an antioxidant polyphenol isolated from olive leaf.
TQ0288	Hexahydrocurcumin	36062-05-2	99.43%
TQ0288	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.
T3834	8-Epideoxyloganic acid	88668-99-9	99.41%
T3834	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during ...
T5426	DMNQ	6956-96-3	99.4%
T5426	DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS...
T72068	SFI003	2361332-90-1	99.37%
T72068	SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in ...
T1661	Crizotinib	877399-52-5	99.35%
T1661	Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.
TN1918	Medicarpin	32383-76-9	99.32%
TN1918	Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of pea...
TN1465	Cannabigerol	25654-31-3	99.23%
TN1465	Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also bi...
T78984	Xanthine oxidase-IN-10	851429-65-7	99.16%
T78984	Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.
T9366	Pyrazoloadenine	2380-63-4	99.10%
T9366	Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.
T72059	S1R agonist 2	150085-21-5	99.04%
T72059	S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
T1633	β-Carotene	7235-40-7	98.99%
T1633	β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and ch...
T0875	Acetylcysteine	616-91-1	98.98%
T0875	Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus th...
T2397	Topiroxostat	577778-58-6	98.95%
T2397	Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
T1363	N-Demethylricinine	21642-98-8	98.94%
T1363	N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor.
T7709	(E/Z)-GSK5182	T7709	98.83%
T7709	(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist...
T5016	Tofogliflozin (hydrate)	1201913-82-7	98.78%
T5016	Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human,...
T8347	Rifamycin S	13553-79-2	98.76%
T8347	Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria
TN1675	Gardenin B	2798-20-1	98.71%
TN1675	Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .