TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
TN3160 |
6-Deoxyisojacareubin
|
26486-92-0
|
98%
|
|
6-Deoxyisojacareubin shows moderate inhibitory activity against the QGY-7703 cell line, with the IC50 value of 9.65 uM; it also possesses potency in the inhibiti...
|
T11740 |
Delcasertib
|
949100-39-4
|
99.96%
|
|
Delcasertib is a potent and selective inhibitor of δ-protein kinase C (δPKC).
|
T6680 |
Staurosporine
|
62996-74-1
|
99.87%
|
|
Staurosporine is a potent PKC inhibitor for PKCα/γ/η (IC50: 2/5/4 nM), less potent to PKCε (73 nM), PKCδ (20 nM) and little action to PKCζ (1086 nM).
|
TQ0198 |
Phorbol 12-myristate 13-acetate
|
16561-29-8
|
99.87%
|
|
Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and PKC activator.
|
T5239 |
Cholesteryl sulfate sodium
|
2864-50-8
|
99.82%
|
|
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a...
|
T2851 |
Daphnetin
|
486-35-1
|
99.82%
|
|
Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), ...
|
T14069 |
A-3 hydrochloride
|
78957-85-4
|
99.79%
|
|
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and c...
|
T1911 |
Afuresertib
|
1047644-62-1
|
99.77%
|
|
Afuresertib is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
|
T0465 |
Ellagic acid
|
476-66-4
|
99.76%
|
|
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
|
T9863 |
PKCiota-IN-2
|
2230055-52-2
|
99.74%
|
|
PKCiota-IN-2 is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 n...
|
T4950 |
1,2-Dipalmitoyl-sn-glycerol
|
30334-71-5
|
99.74%
|
|
1,2-Dipalmitoyl-sn-glycerol is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.
|
T2441 |
TAS-301
|
193620-69-8
|
99.69%
|
|
TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.
|
T7648 |
HA-100
|
84468-24-6
|
99.69%
|
|
HA-100 is an inhibitor of protein kinase
|
T20168 |
Aurothiomalate sodium
|
12244-57-4
|
99.66%
|
|
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium is a potent and selective inhibitor...
|
TN1557 |
Decursinol angelate
|
130848-06-5
|
99.65%
|
|
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of th...
|
T7501 |
Iso-H7 dihydrochloride
|
140663-38-3
|
99.64%
|
|
Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.
|
TN1513 |
Clitorin
|
55804-74-5
|
99.63%
|
|
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.
|
TP1945L1 |
Pep2m, myristoylated acetate
|
TP1945L1
|
99.62%
|
|
Pep2m, myristoylated acetate is a Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA rec...
|
T3050 |
ML-7 hydrochloride
|
110448-33-4
|
99.61%
|
|
ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also...
|