Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T80604 | Duligotuzumab | 1314238-96-4 | 98% |
Duligotuzumab
|
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1]. | ||||
T80612 | Pimurutamab | 2251771-76-1 | 98% |
Pimurutamab
|
Pimurutamab, a humanized IgG1-κ antibody, selectively targets the epidermal growth factor receptor (EGFR) and is primarily produced by CHO-K1 cells [1]. | ||||
T80614 | Serclutamab | 2140172-41-2 | 98% |
Serclutamab
|
Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR). It is primarily pro... | ||||
T80643 | BEBT-109 | 2050906-40-4 | 98% |
|
BEBT-109 is a potent selective inhibitor of pan-mutant EGFR with enhanced pharmacokinetic properties, suitable for research on various mutant-EGFR-driven non-sma... | ||||
T80748 | YS-363 | 2470908-90-6 | 98% |
|
YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (IC5... | ||||
T81596 | Os30 | 98% |
|
|
Os30 is a potent fourth-generation EGFR inhibitor, specifically targeting the EGFRC797S-TK mutation with IC50 values of 18 nM for EGFRDel19/T790M/C797S TK and 11... | ||||
T81679 | Nezutatug | 2673271-78-6 | 98% |
Nezutatug
|
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1]. | ||||
T81739 | Multi-target kinase inhibitor 2 | 98% |
|
|
Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values b... | ||||
T82491 | EGFR-IN-90 | 98% |
|
|
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an IC50 of 5.1 nM and effectively inhi... | ||||
T82492 | EGFR/HER2/DHFR-IN-3 | 98% |
|
|
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.09... | ||||
T82493 | EGFR/HER2/DHFR-IN-2 | 98% |
|
|
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anti... | ||||
T11157 | EGFR-IN-1 | 1625677-63-5 | 98% |
|
EGFR-IN-1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. EGFR-IN-1 is an orally a... | ||||
TQ0293 | AV-412 free base | 451492-95-8 | 98% |
|
AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2). | ||||
TMA1944 | Protopine hydrochloride | 6164-47-2 | 98% |
|
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracell... | ||||
T6046 | (E/Z)-CP-724714 | 537705-08-1 | 98% |
|
(E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent and selective orally active inhibitor of ErbB2 (HER2)[1].... | ||||
TN3525 | Boehmenan | 57296-22-7 | 98% |
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ... | ||||
T10256 | Afatinib D6 | 1313874-96-2 | 98% |
|
Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor. | ||||
TN1871 | Ligustroside | 35897-92-8 | 98% |
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Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustrosid... | ||||
T35334 | CH7233163 | 98% |
|
|
CH7233163 is a useful organic compound for research related to life sciences and the catalog number is T35334. | ||||
T19489 | O-Desmethyl gefitinib D8 | T19489 | 98% |
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O-Desmethyl gefitinib D8 is a deuterium labeled O-Desmethyl gefitinib that is an active metabolite of Gefitinib in human plasma. |