TN2191 |
Scutebarbatine A
|
176520-13-1
|
98%
|
|
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspa...
|
TN2116 |
Pteropodine
|
5629-60-7
|
98%
|
|
Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects,...
|
TN1875 |
Liriodenine
|
475-75-2
|
98%
|
|
Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can ...
|
T16042 |
Metaldehyde
|
108-62-3
|
98%
|
|
Metaldehyde is used for snails and other gastropods pesticide against.
|
T11974 |
Mcl1-IN-12
|
2042211-12-9
|
98%
|
|
Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.
|
TN5201 |
Uncarinic acid E
|
277751-61-8
|
98%
|
|
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resul...
|
TN2149 |
Reynosin
|
28254-53-7
|
98%
|
|
Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reci...
|
T14213 |
Tapotoclax
|
1883727-34-1
|
98%
|
|
AMG-176 is a MCL-1 inhibitor (Ki: 0.13 nM).
|
TN2106 |
Protodeltonin
|
94992-08-2
|
98%
|
|
Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhi...
|
TN1617 |
Ergosta-4,6,8(14),22-tetraen-3-one
|
19254-69-4
|
98%
|
|
Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatoce...
|
TN3618 |
Cedrin
|
75513-81-4
|
98%
|
|
Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative s...
|
TN4341 |
IVHD-valtrate
|
28325-56-6
|
98%
|
|
VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a ...
|
TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
|
T11975 |
PROTAC Mcl1 degrader-1
|
2163793-38-0
|
98%
|
|
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide t...
|
TN2002 |
Obovatol
|
83864-78-2
|
98%
|
|
Obovatol has antioxidant, neuroprotective, antiinflammatory, antithrombotic and antitumour effects, it is a potent NF-κB inhibitors for Alzheimer's disease treat...
|
TN2691 |
2',3'-Dehydrosalannol
|
97411-50-2
|
98%
|
|
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits ca...
|
TN1093 |
Ginsenoside F4
|
181225-33-2
|
98%
|
|
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
|
TN1532 |
Crenulatin
|
63026-02-8
|
98%
|
|
Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L ...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4604 |
Myricanone
|
32492-74-3
|
98%
|
|
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
|