TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
T10274 |
AKT-IN-2
|
1295514-91-8
|
98%
|
|
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
|
T11743 |
Kanosamine hydrochloride
|
57649-10-2
|
98%
|
|
Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits...
|
TN4263 |
Isoangustone A
|
129280-34-8
|
98%
|
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
|
TN4390 |
Kihadanin B
|
73793-68-7
|
98%
|
|
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
|
TN1376 |
α-Solanine
|
20562-02-1
|
98%
|
|
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
|
TN1235 |
3,4,5-Tricaffeoylquinic acid
|
86632-03-3
|
98%
|
|
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like rece...
|
TN3691 |
Communic acid
|
2761-77-5
|
98%
|
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
|
TN3525 |
Boehmenan
|
57296-22-7
|
98%
|
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
TN1458 |
Buddlejasaponin IV
|
139523-30-1
|
98%
|
|
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
|
TN4244 |
Icariside B1
|
109062-00-2
|
98%
|
|
Icariside B1 shows inhibitory effects on LPS-induced NO production in RAW264.7 cells.
|
TN1889 |
Lupalbigenin
|
76754-24-0
|
98%
|
|
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
|
TN4506 |
(+)-Matairesinol
|
148409-36-3
|
98%
|
|
(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle.
|
TN3139 |
5α-Hydroxycostic acid
|
132185-83-2
|
98%
|
|
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
|
T15056 |
DB07107
|
552332-71-5
|
98%
|
|
DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
TN2328 |
Zeylenone
|
193410-84-3
|
98%
|
|
Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing...
|
T75078 |
Antitumor agent-86
|
2907704-65-6
|
98%
|
|
Antitumor agent-86 (compound 5a) demonstrates efficacy against MCF-7 breast cancer cells, manifesting an inhibitory concentration (IC 50) of 2.62 µM. It promotes...
|