TN5431 |
Icariside E4
|
126253-42-7
|
98%
|
|
Icariside E4 is a natural compound derived from Ulmus minor that acts via AMPK phosphorylation and inhibition of MID1IP2 hypolipidation in HepG1 cells.Icariside ...
|
T13371 |
YM-53601 free base
|
182959-28-0
|
98%
|
|
YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.
|
T8200 |
Ginkgolide K
|
153355-70-5
|
99.98%
|
|
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
|
T3881 |
Vaccarin
|
53452-16-7
|
99.97%
|
|
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation...
|
T5552 |
Methyl cinnamate
|
103-26-4
|
99.95%
|
|
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
|
TN1836 |
Kudinoside D
|
173792-61-5
|
99.88%
|
|
Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.
|
TN1140 |
Onjisaponin B
|
35906-36-6
|
99.88%
|
|
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-sy...
|
TN1828 |
Kahweol
|
6894-43-5
|
99.86%
|
|
Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degrad...
|
T3625 |
Bempedoic acid
|
738606-46-7
|
99.84%
|
|
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects as...
|
T13411 |
ZLN024
|
723249-01-2
|
99.82%
|
|
ZLN024 is an activator of AMPK allosteric. ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive α1 subunit truncations α1 (1-394) and α1 (...
|
T0740 |
Metformin hydrochloride
|
1115-70-4
|
99.81%
|
|
Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the...
|
T5576 |
YKL-06-061
|
2172617-15-9
|
99.81%
|
|
YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.
|
T8526 |
Metformin
|
657-24-9
|
99.77%
|
|
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensit...
|
T62238 |
AMPK activator 4
|
2493239-46-4
|
99.75%
|
|
AMPK activator 4 is a potent and selective AMPK activator that does not inhibit mitochondrial complex I. AMPK activator 4 selectively activates AMPK in muscle ti...
|
TN1499 |
Cimiracemoside C
|
256925-92-5
|
99.73%
|
|
Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.
|
T0858 |
Flufenamic acid
|
530-78-9
|
99.71%
|
|
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint ...
|
T3904 |
Gomisin J
|
66280-25-9
|
99.69%
|
|
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
|
T8740 |
COH-SR4
|
73439-19-7
|
99.67%
|
|
COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation. COH-SR4 modulates amp-dependent kinase (ampk)-mammalian...
|
T13354 |
Xanthoangelol
|
62949-76-2
|
99.67%
|
|
Xanthoangelol, which can be extracted from Angelica keiskei, inhibits obesity-induced inflammatory responses.Xanthoangelol has antimicrobial activity, inhibits m...
|
T13265 |
Urolithin B
|
1139-83-9
|
99.64%
|
|
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical frui...
|