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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8785 | HALOFUGINONE LACTATE | DNA/RNA Synthesis , TGF-beta/Smad | |
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1012 | Febrifugine | IL Receptor , Anti-infection , Parasite | |
Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity . | |||
TN1012L | Febrifugine dihydrochloride | ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,Pildralazine dihydrochloride | Parasite |
Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases. | |||
TN1145 | Isofebrifugine | Parasite | |
Isofebrifugine is an alkaloid from the plant Changshan of the Saxifrage family with antimalarial and anti-infectious activity. | |||
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... |